iosr-JDMS   Volume-18 ~ Issue-5 ~ May-2019

Abstract: Introduction:Epidemiological studies have shown a higher risk of cardiovascular mortality associated with early menopause, but the relation between menopausal age and extent of coronary artery disease after menopause is unknown. We assessed the relation between menopausal age and extent of coronary disease in postmenopausal women with an acute coronary syndrome.
Methods:A prospective study was conducted in patients 55 years old undergoing coronary angiography for an acute coronary syndrome. Enrollment was stratified by sex (women/men ratio 2:1) and age (55-64, 65-74, 75-85, and >85 years). Women were administered menopause questionnaires during admission. An independent core lab quantified coronary artery disease extent using the Gensini Score, which classifies both significant (>50%) and no significant lesions. Linear correlation was used to appraise the association between the Gensini score and menopausal age........

Keywords :Atherosclerosis; Coronary angiography; Coronary artery disease; Menopause

[1]. Mehta LS, Beckie TM, DeVon HA, et al; on behalf of the AmericanHeart Association Cardiovascular Disease in Women and SpecialPopulations Committee of the Council on Clinical Cardiology, Councilon Epidemiology and Prevention, Council on Cardiovascular andStroke Nursing, and Council on Quality of Care and OutcomesResearch. Acute myocardial infarction in women: a scientific statementfrom the American Heart Association. Circulation. 2016; 133:916-947.
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Abstract: This was an observational prospective experimental study was distributed in Dhaka Shishu Hospital (DSH) from July 2015 to June 2017. Our aim was to observe cardiac functional status in Neonates by measuring of serum Troponin-I and Echocardiographic changes. A total of 75 cases were selected for the study period. The enrolled patients were grouped into HIE Stage-I, HIE Stage-II, and HIE Stage-III. For all patients in each group Level of Cardiac troponin I, ECG changes, and Echocardiographic parameters were observed and recorded.Twenty cases were found to be in HIE Stage-I, twenty-four cases in HIE stage-II and thirty-one Cases in HIE stage-III. Among....

Key Words: Echocardiographic, Crown Heel Length (CHL), Occipital Frontal Circumference (OFC), Myocardial, Dysfunctional, Serum, Cardiac Troponin

[1]. Nestaas E, Støylen A, Fugelseth D. Myocardial performance assessment in neonates by one-segment strain and strain rate analysis by tissue Doppler - a quality improvement cohort study. BMJ Open [Internet]. 2012;2(4): e001636. Available from: http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2012-001636 : 1—9.
[2]. Dambalkar G. Multiorgan dysfunction in neonates with perinatal asphyxia. MD Dissertation. Rajive Gandhi university of Health science, Karnataka. Bangalore. 2010.
[3]. P.S. Rajakumar, B. Vishnu Bhat, M.G. Sridhar, J. Balachander, B.C. Konar, P. Narayanan and G. Chetan. Cardiac Enzyme Levels in Myocardial Dysfunction in Newborn with Perinatal Asohyxia. Indian J Pediatr 2008; 75 (12): 1223—1225.
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Abstract: Shoulder pain is the third most common musculoskeletal complaint in the general population, and accounts for 5% of all musculoskeletal consultations. It is second only to knee pain for referrals to the Orthopedics. Shoulder pain can be acute or chronic. Nonacute shoulder pain is a common medical condition, particularly in middle-aged and older adults [1, 2]. Nonacute, or chronic, shoulder pain is defined as pain lasting at least 6 months, often without a definite inciting traumatic event. There are many causes of nonacute shoulder pain. Common causes of nonacute shoulder pain, listed in order from the most to the least common, include rotator cuff impingement, tendinosis, and tears; adhesive capsulitis; subacromial-subdeltoid bursitis; calcific tendinosis; glenohumeral........

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Abstract: Introduction: Telomerase, an RNA dependent DNA polymerase, directs the synthesis of telomeric DNA repeats and compensates for the loss of telomeres during cell division, provides the molecular basis for unlimited proliferative potential. This telomerase is up regulated in many carcinomas. Objectives: Present study was aimed at the quantification of telomerase activity in normal oral mucosa and in oral premalignant lesion (leukoplakia) and the comparison of telomerase activity in the two groups. As it is difficult to predict the chances of malignant transformation of oral premalignant lesions only on the basis of dysplasia, an attempt has been made.......

Keywords: Telomerase; Oral premalignant disorders; Quantification; Oral leukoplakia; Prognostic marker

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[5]. Reibel J. Prognosis of Oral Pre-Malignant Lesions: Significance Of Clinical, Histopathological, And Molecular Biological Characteristics. Crit Rev Oral Biol Med. 2003; 14 (1):47-62.

Abstract: Background: The diagnosis of breast lump is very important for achieving best result, it needs multi-disciplinary approach, it include triple assessment - Clinical, Radiological and Pathological examination is gold standard technique for diagnosis of breast diseases, the present study was analyze the effectiveness of FNAC in detecting breast diseases. FNAC of Breast Lump is basic and important, minimal invasive diagnostic tool pre-operatively for early and accurate diagnosis, & has ability to give rapid diagnostic information high correlation to that of frozen Section, hence it reduced need of frozen section biopsy meanwhile both aspirator and interpreter should be the same person with adequate sample. Cytological study carried out as per the worldwide accepted five tier system. Aims & objective: 1.To Asses Variant of Breast Lump. 2. To Asses Diagnostic Accuracy and Adequacy of Sample. 3. Cytological features of Smear. Material & Methods: This is a Prospective Study, from October 2016............

Key words: Benign breast diseases, Fine Needle Aspiration Cytology (FNAC), Fibroadenoma

[1]. Kazi Farzana Khanam, Nasima Akter, N., Tarana Tabashum, Abu Khalid Muhammad Maruf Raza, Asma UI Hosna, Farzana Rahman, Afroza Begum ―Clinicopathologic Study of Various Breast Lesions by Fine Needle Aspiration Cytology (FNAC)‖. Journal of Current Surgery, Volume 8, no 3- 4. Nov 2018.

[2]. Svante R. Orell, Gregory F. Sterrett. Chapter 7 ‗Breast' by Joan Cangiarella and Aylin Simsir, Book ―Orell and Sterrett's Fine Needle Aspiration Cytology‖ 5th Edi, page no 157-209.

[3]. Bailey & Loves ―Short Practice of Surgery‖ 27th Edition Volume II Page No. 860 – 870.

[4]. Pradhan M, Dhakal HP, ―Study of breast lump of 2246 cases by FNAC‖ JNMA J Nepal MED assoc. 2008;47(172):205-209.
[5]. Garbar C, Cure H. ―Fine-needle aspiration cytology can play a role in neoadjuvant chemotherapy in operable breast cancer‖. ISRN Oncol. 2013; 2013:935796, 5 pages.

Abstract: Members of TGF-β superfamily participate in controlling hair apoptosis, and the roles of those factors in the hair cycle have not been sufficiently clear. BMPs which belong to the TGF-β superfamily also play critical roles in governing hair growth. In the process of controlling hair growth through the interacting between BMPs and noggin, noggin not only acts as an inhibitor of BMP-2 and 4 but influents the wavy expressions of BMP-2 and 4. Furthermore, BMPs are similar with TGF-β1, 2, 3 in structures and biologic characters. We present the positions of TGF-β1, 2, 3, and among those factors TGF-β1, 2 have some consistency with the positions.........

Key Words: Bone morphogenetic protein, Bone morphogenetic protein receptor, Hair cycle, Noggin, Transforming growth factor beta

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[3] Plikus, Maksim V, et al. Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration, NATURE 451(7176), 2008, 340-344.
[4] Soma, T, Y. Tsuji, and T. Hibino . Involvement of transforming growth factor-beta2 in catagen induction during the human hair cycle, Journal of Investigative Dermatology, 118(6), 2002, 993-997.
[5] Foitzik, Kerstin, et al, Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression (Catagen) by Upregulation of Transforming Growth Factor-|[beta]|2 in the Dermal Papilla, Journal of Investigative Dermatology 124(6), 2005, 1119-26.

Abstract: Necessary is the mother of invention. In my entire lifespan i.e. for the last 40 years of life has been spent in search of why, where, when, whom. I had faced these problems and tried to find solution for myself. 10 years back I had postulated a hypothesis that by disintegrating an atom of one liter water and we can get electricity by that process, by using that electricity we can prepare hybrid electric car. That patent had been taken by Japanese govt because of my lack of knowledge regarding where and whom I have to submit. Till today I am having the same problem and tried answer for why, where, when etc. My journey started like this. In my collage days I had...........

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Abstract: Aim: The aim of this study was to examine the role of different ultra-translucent monolithic zirconia on marginal gap values for laminate veneers. Materials and methods: Thirty prepared fiber reinforced resin abutments were milled and used in this study. Thirty laminate veneers were milled from different ultra-translucent monolithic zirconia blanks and divided into 3 groups (n=10) [group D (DDcubex2), group P (Prettau Anterior) and group K(KATANA UTML)] then sintered. All the veneers were sandblasted, treated by ceramic primer and cemented to the abutments. All specimens were collected for evaluation of marginal adaptation using scanning electron microscope (SEM). Results: Statistical difference...........

Key Words: Monolithic translucent zirconia, laminate veneers, marginal adaptation, SEM

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[4]. Christensen GJ. The ceramic crown dilemma. The Journal of the American Dental Association. 2010; 141: 1019-1022.
[5]. Beuer F, Stimmelmayr M, Gernet W, Edelhoff D, Güth J-F, Naumann M. Prospective study of zirconia-based restorations: 3-year clinical results. Quint inter. 2010;41..

Abstract: The characteristics of Kawasaki disease have significantly changed in pediatric age group during last few decades. The present study was conducted to study the clinical profile and outcome and risk factors of Kawasaki disease in children in the largest children hospital of Bangladesh.This observational prospectivestudy was conducted in cardiology wardwith a diagnosis of Kawasaki disease from April 2014 to March 2019. Forty three (43) children aged between 3 months to 10 years were studied.Kawasaki disease is more prevalent among male child (72%). Most commonly encountered risk factor for cardiovascular involvement especially coronary dilatation or aneurysmal change is more observed in younger age of presentation. Fever, rash, conjunctivitis, erythema and edema of limbs, periungual skin desquamations are the presenting features. Cardiovascular involvement of left main coronary artery..........

Key Words: Characteristics, Cardiovascular Involvement, Aneurysm, IVIG, Treatment, Outcome

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[5]. Newberger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC,et al: Diagnosis, treatment and long term management of Kawasaki disease: a statement for health professionals from the committee on rheumatic fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association, Circulation 2004;110:27-47.

Abstract: Background: Lymphadenopathy refers to enlargement of lymph nodes. It is a common clinical presentation. It can be caused due to various etiologies ranging from infections to malignancies. Fine Needle Aspiration Cytology can be done easily on superficial lymphadenopathies as they are accessible. FNAC is a simple, cost effective procedure which is minimally invasive. It helps in diagnosing lymphadenopathies due to various etiologies and plan the treatment accordingly. Tuberculosis is the most common cause of lymphadenopathy in India. Aims and objectives: To study cytomorphological patterns of lymphadenopathy due to various etiologies and to know the frequency of various diseases.......

Key Words: Fine Needle Aspiratin Cytology, Granulomatous, Lymphadenopathy

[1]. SachinA, Anjalee G Ovhal et al. Study of fine needle aspiration cytology of lymph node in rural area of bastar district, Chattisgarh. Med J of D Y Patil Univ 201710;2:143-7.
[2]. Debjani Mallik, Rabi dra Nathprasad et al. Spectrum of lymph node lesions by fine needle aspiration cytology in worker population in eastern India. Int J of occupational hygiene.2015;7139-145.
[3]. Ramanan Duruswamia, Sujatha Margam et al, Spectrum of pathologies on FNAC evaluation of peripheral lymph nodes at a tertiary care center in Hyderabad: a retrospective study. Int J of advances in Med 20174(1): 27-33.
[4]. Gayatri MN, Sakshi Chaurasia et al. Pattern of lymphadenopathy in fine needle aspiration cytology: a retrospective study. Int J Res Med Sci.2015;3(6):1416-19.
[5]. Prabhakar Patro, Priyanka Lad et al. Spectrum of lesions in lymph nodes – A cytological study.ijhsr 2018;8(11):75-81..