iosr-JDMS   Volume-20 ~ Issue-9 ~ Sep. 2021

Abstract: SARS-Cov-2 is the causative agent of the covid-19 pandemic. Vaccination is very effective and better way to decrease mortalities and prevent serious illness associated with covid-19. All vaccines have side effects that need to be reported and investigated to weigh the anticipated benefits and risks. Here we present a case of 45 years old female patient with a history of hypertension and DM and a history of vaccination for SARS-Cov-2 first dose 15 days back. Then she had fever for 2 days later she developed hematuria. on evaluation all investigations were done to rule out relevant conditions. in view of recent vaccination, covid vaccine-induced hemolytic anemia is considered with ruled out all relevant causes of hematuria and fever. so based on this report we are finally concluding that clinicians should be aware of possible adverse effects and management related to covid-19 vaccines..

[1]. Brito S, Ferreira N, Mateus S, Bernardo M, Pinto B, Lourenço A, et al. A case of autoimmune hemolytic anemia following COVID-19 messenger ribonucleic acid vaccination. Cureus. 2021;13(5):e15035.
[2]. Dhaliwal G, Cornett PA, Tierney LM Jr. Hemolytic anemia. Am Fam Physician. 2004;69(11):2599–606.
[3]. Longdom.org. [cited 2021 Aug 30]. Available from: https://www.longdom.org/scholarly/haemolytic-anaemia-journals-articles-ppts-list-2547.html
[4]. COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria Gloria F. Brodsky1.
[5]. Quinn R, Murakhovskaya I. SARS-CoV-2 and autoimmune cytopenia. Hemato. 2021;2(3):463–76

Abstract: Background: The COVID-19 pandemic, is an ongoing global caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus was first identified in December 2019 in Wuhan, China. The World Health Organization declared a Public Health Emergency of International Concern regarding COVID-19 on 30 January 2020, and later declared a pandemic on 11 March 2020. The first case of the COVID-19 pandemic in the Indian state of Maharashtra was confirmed on 9 March 2020. Severe COVID-19 disease mainly affects adults and otherwise healthy children and young adults appear to be relatively spared. The aim of this study was to describe spectrum of COVID-19 during second Wave in children. Materials and Methods: Hospital based retrospective....

[1]. WHO Director-General's opening remarks at the media briefing on COVID19 -March 2020
[2]. COVID-19 puts societies to the test (Editorial). Lancet Public Health. 2020;5: e235.
[3]. Tambe MP, Parande MA, Tapare VS, Borle PS, Lakde RN, Shelke SC, BJMC COVID Epidemiology group. An epidemiological study of laboratory confirmed COVID-19 cases admitted in a tertiary care hospital of Pune, Maharashtra. Indian J Public Health 2020;64, Suppl S2:183-7
[4]. Zhang L, Peres TG, Silva MVF, Camargos P. What we know so far about Coronavirus Disease 2019 in children: A meta-analysis of 551 laboratory-confirmed cases. Pediatric Pulmonol. 2020; 55:2115-27.
[5]. Liguoro I, Pilotto C, Bonanni M, et al. SARS-COV-2 infection in children and newborns: A systematic review. Eur J Pediatr. 2020; 179:1029-46.

Abstract: Background: Rehabilitation of missing teeth with fixed dental prosthesis has been practiced since many years. Fixed dental prosthesis are still preferred than removable dentures in most of the reliable cases due to strength, aesthetics, satisfactory retention and psychological comfort. The cements used for luting the crowns has a significant role in the success of fixed prosthesis. It is a challenging task in selecting the proper cements from the diverse range of materials available today. Aim: The aim of the study is to evaluate the knowledge, attitude, and practice of cements/ luting agents used for fixed prosthesis among Indian dental practitioners. Materials and Methods: The study involved a survey of 171 dental practitioners all among India. A questionnaire on the knowledge, attitude......

Key word: dental cements, glass ionomer cements, Zirconia, lithium disilicate crowns, fixed dental prosthesis

[1]. Shillingburg HT Jr, Hobo S, Whitsett LD, Jacobi R, Brackett,SE. Fundamentals of fixed prosthodontics. 3rd ed. Chicago: Quintessence; 1997. p. 85-118.
[2]. Rosentiel SF, Land MF, Fujimoto J. Contemporary Fixed Prosthodontics, ed 3. St Louis:Mosby, 2001:70.
[3]. Lawson NC, Litaker MS, Ferracane JL, Gordan VV, Atlas AM, Rios T, Gilbert GH, McCracken MS, National Dental Practice-Based Research Network Collaborative Group. Choice of cement for single-unit crowns: findings from The National Dental Practice-Based Research Network. J Am Dent Assoc 2019;150:522–530.
[4]. O'Brien W. Dental materials and their selection. 3rd edition.Chicago. Quintessence;2002,p 133-55
[5]. Blatz MB, Sadan A, Kern M. Resin-ceramic bonding: A review of the literature. J Prosthet Dent 2003;89:268-74.

Abstract: Electrospinning is a technique used to fabricate polymeric fibres of nanometre dimensions by applying high voltage difference to a syringe loaded with polymeric solution. This technique has enabled production of high-quality tissue engineering scaffolds for application in periodontal regeneration and other biomedical applications. Technique depends on various parameters like voltage difference, jet speed, distance between the collector plate etc. The electro spun nanofibers possess superior physical, chemical, biological and mechanical properties which are noteworthy. The clinical application of electro spun nanofibers span across all fields of biomedical science which includes tissue engineering and regenerative medicine, diagnostics, drug delivery and wound healing. Of these specific interest......

Key words: Electrospinning, Nanofibers, Periodontics, Regeneration, Tissue Engineering

[1]. Graziani F, Karapetsa D, Alonso B, Herrera D. Nonsurgical and surgical treatment of periodontitis: how many options for one disease? Periodontol 2000. 2017 Oct;75(1):152–88.
[2]. Cochran DL, Cobb CM, Bashutski JD, Chun Y-HP, Lin Z, Mandelaris GA, et al. Emerging Regenerative Approaches for Periodontal Reconstruction: A Consensus Report From the AAP Regeneration Workshop. Journal of Periodontology. 2015 Feb;86(2-s):S153–6.
[3]. Bhardwaj N, Kundu SC. Electrospinning: A fascinating fiber fabrication technique. Biotechnology Advances. 2010 May;28(3):325–47.
[4]. Zhang X, Reagan MR, Kaplan DL. Electrospun silk biomaterial scaffolds for regenerative medicine. Advanced Drug Delivery Reviews. 2009 Oct;61(12):988–1006.
[5]. iang D, Hsiao BS, Chu B. Functional electrospun nanofibrous scaffolds for biomedical applications. Advanced Drug Delivery Reviews. 2007 Dec;59(14):1392–412

Abstract: Periodontal regenerative therapy results in the augmentation of the attachment and bone level in addition to reduction in pocket depth with minimal soft tissue recession. Various regenerative approaches such as GTR, bioresorbable grafts, 3-D printing scaffolds were developed, of which 3-D printing is the most innovative technology. In 3D printing, an ideal structure has been built layer by layer from CAD/digital 3D model. 3D scaffolds in the form of bone graft substitutes are found to be advantageous over commonly used grafting materials. Various biomaterials such as natural, synthetic, bioceramics and metals are used for preparing these scaffolds. Biomaterials can be combined to regenerate the complex structure of the bone-PDL-cementum apparatus by designing layered materials and cells to biomimetically regenerate periodontal structures completely and synchronously. New biomaterials are dramatically broadening the options for advanced periodontal regeneration therapeutics and various old biomaterials are being modified to elicit better biological and systemic responses.

Keywords: Biomaterials, Natural and synthetic biomaterials, 3D printing, Periodontics, Regeneration, Scaffolds

[1]. Sculean A. Current clinical concepts in regenerative periodontal therapy. 2017;8.
[2]. Gul M, Arif A, Ghafoor R. Role of three-dimensional printing in periodontal regeneration and repair: Literature review. J Indian Soc Periodontol. 2019;23(6):504.
[3]. Department of Preventive Dental Sciences, College of Dentistry, Gulf Medical University, United Arab., Reddy MS, Shetty SR, Department of Oral and Craniofacial Health Sciences, College of Dental Medicine University of Sharjah, University City Sharjah,United Arab Emirates., Shetty RM, Department of Clinical Sciences, College of Dentistry, Ajman University, UAE., et al. Focus on periodontal engineering by 3D printing technology – A systematic review. J Oral Res. 2020 Dec 30;9(6):522–31.
[4]. Raveau S, Jordana F. Tissue engineering and three-dimensional printing in periodontal regeneration. 2020;21.
[5]. Brunello G, Sivolella S, Meneghello R, Ferroni L, Gardin C, Piattelli A, et al. Powder-based 3D printing for bone tissue engineering. Biotechnology Advances. 2016 Sep;34(5):740–53.

Abstract: A solitary bone cyst is a non-neoplastic osseous lesion comprising 1% of all the cysts affecting the jaws. The lesion is mainly diagnosed in young patients most frequently during the second decade of life. The majority of them are located in the mandibular body between the canine and the third molar. Clinically, the lesion is asymptomatic and is often accidentally discovered on routine radiological examination. The definite diagnosis of traumatic cyst can only be determined at surgery. Often, the material for histological examination may be scanty or non-existent. This article presents a well-documented case of a solitary bone cyst involving the body of mandible in a 14-year-old patient with no history of previous trauma. Simple curettage of the bone cavity resulted in the resolution of the lesion with progressive osseous regeneration. No evidence of recurrence was noted 6 months after the treatment.

Keywords: Solitary bone cyst, Non-epithelial, Traumatic bone cyst, Hemorrhagic bone cyst, Idiopathic bone cyst, Osteodystrophic cyst, Mandible

[1]. Vidya Ajila et al. Unusual presentation of Solitary bone cyst – A case report. Nitte University Journal of Health Science. Vol. 4, No. 1 , March 2014.
[2]. Brenda L. Nelson et al. Solitary Bone Cyst. Head and Neck Pathol (2010 ) $ : 208-209.
[3]. Arati S Neeli et al. Solitary bone cysts of the mandible : Two case reports and a review of literature. World Journal of Dentistry , July – September 2013 ; 4 (3) : 193-197.
[4]. Zaid H. Baqain et al. Recurrence of a solitary bone cyst of the mandible : case report. British Journal of Oral and Maxillofacial Surgery (2005) 43 , 333-335.
[5]. Joseph L. Bernier and Surinder N. Bhaskar. Aneurysmal bone cysts of the mandible . Volume 11 , Number.

Abstract: Background: Scorpion sting envenomation is a life threatening emergency if untreated. The main objective is to study the clinical profile ,outcome and efficacy of prazocin in scorpion sting envenomation in children. Materials&Methods: A prospective study was conducted over a period of one year from May 2019 to November 2000 in The Department of Peadiatrics in ANMMCH Gaya. Case records were analyzed for age and sex of the patient; site of scorpion sting, time lapsed from the scorpion sting to hospitalization, clinical manifestations , treatment and outcome were recorded. Results: During the study period, 100 children were admitted for scorpion sting. Majority of the children are from rural area,male sex, and stung in lower limb mostly in summer. Local pain at the site of sting and sweating are the commonest local symptoms and systemic.....

Keywords: Scorpion sting envenomation, Prazocin, alpha blocker

[1]. Sarthi M. et al. Clinical Study of scorpion sting envenomation. Int J Contemp Pediatr. 2019 May; 6(3): 1154-1157. .Singhal A. et al. Epidemiology, Clinical Presentation and Final Outcome of Patients with Scorpion Bite. Journal of clinical and diagnostic research. 2009; June; 3(3): 1523 - 1528
[2]. Tarachand saini et al. Scorpion Bite Causing Acute Severe Myocarditis: A Rare Complication. Indian Journal Of Clinical Practice, vol 23,No 3, 2012.
[3]. Bawaskar HS, Bawaskar PH.Prazocin in management of cardiovascular manifestations of scorpian sting.Lancet 1986;1:510-1.
[4]. Bawaskar HS, Bawaskar PH.Indian red scorpionenvenoming,Indian J Pediatr. 1998;65:383-91.
[5]. Ismail M. The scorpion-envenoming syndrome. Toxicon. 1995;3:825-58.
[6]. Chi PJP. Emerging options for the management of scorpion stings. Drug Des Devel Ther. 2012;6:165- 73...

Abstract: Venous thromboembolism is an uncommon but spectacular occurrence which is the most serious cause during pregnancy and postpartum maternal death and morbidity. Compared to a pregnant incidence, the risk of venous thromboembolism is particularly significant during the postpartum period (up to 6 weeks following birth) (1). Symptoms that signal pulmonary embolism must be closely examined, failure to analyse symptoms is a consistent result in maternal fatalities (2). A 21-year-old woman who has recently born a boy ten days before being admitted to an Indian hospital of tertiary care and has been presented to the department of cardiology with major complaints of chest pain, shortness of breath, pedal oedema, and who was not able to walk the last 3 days. All the essential investigations were proposed and diagnosed with venous thromboembolism in postpartum diseases..

Keywords: Venous Thrombolism; Postpartum; Pedal oedema.

[1]. Morris JM, Algert CS, Roberts CL. Incidence and risk factors for pulmonary embolism in the postpartum period. J Thromb Haemost. 2010;8(5):998–1003.
[2]. Mclintock C, Brighton T, Chunilal S, Dekker G, Mcdonnell N, Mcrae S, Muller P, Tran H, Walters BN, Young L. Recommendations for the diagnosis and treatment of deep venous thrombosis and pulmonary embolism in pregnancy and the postpartum period. Australian and New Zealand Journal of Obstetrics and Gynaecology. 2012 Feb;52(1):14-22.
[3]. Sultan AA, Tata LJ, West J, Fiaschi L, Fleming KM, Nelson-Piercy C, Grainge MJ. Risk factors for first venous thromboembolism around pregnancy: a population-based cohort study from the United Kingdom. Blood, The Journal of the American Society of Hematology. 2013 May 9;121(19):3953-61.
[4]. Heit JA, Kobbervig CE, James AH, Petterson TM, Bailey KR, Melton III LJ. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study. Annals of internal medicine. 2005 Nov 15;143(10):697-706.
[5]. Pomp ER, Lenselink AM, Rosendaal FR, Doggen CJM. Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study. J Thromb Haemost. 2008;6(4):632–7.

Abstract: Background: Glycated haemoglobin (HbA1c) is considered a gold-standard measure of chronic glycaemia in diabetic patients. Changes in renal profile is also well related with severity of DM as ruled by HbA1c.Serum creatinine and serum urea are recognised as ideal markers to co-relate the progression of diabetic nephropathy Aims and objectives: To investigate the association of serum urea and creatinine with glycosylated Haemoglobin in type 2DM patients. Materials and Methods: A cross-sectional study was conducted among the patients with a history of type 2 Diabetes mellitus for the past 10 years who were attending diabetic clinic at MES Medical College and hospital, Perinthalmanna, Malappuram district.....

Keywords: Association, HbA1c, serum creatinine, serum urea, Type2 DM

[1]. Bamanikar SA, Bamanikar AA, Arora A. Study of Serum urea and Creatinine in Diabetic and non-diabetic patients in a tertiary teaching hospital. The Journal of Medical Research. 2016;2(1):12-5.
[2]. Kumari, P. L. Estimation of Lipid Profiles of Patients with Type-2 Diabetes Mellitus at Adoor, Kerala. Academia Journal of Medicine, (2020) 3(2), 6-9
[3]. Abdelsalam KA, ME A. Correlation between urea level and HbA1c level in type 2 diabetic patients. Sub Med Lab. 2011;1:1-6.
[4]. Mehta SR, Kashyap AS, Das S. Diabetes mellitus in India: The modern scourge. Medical journal armed forces India. 2009 Jan 1;65(1):50-4.
[5]. Amartey NA, Nsiah K, Mensah FO. Plasma levels of uric acid, urea and creatinine in diabetics who visit the Clinical Analysis Laboratory (CAn-Lab) at Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. Journal of clinical and diagnostic research: JCDR. 2015 Feb;9(2):BC05

Abstract: Background: Vulvovaginal candidiasis (VVC) is the most common cause of fungal infection in reproductive age group. It is of special concern due to its chronic course and frequent recurrence due to inappropriate or incomplete treatment. Due to emergence of antifungal drug resistance, traditional practice of empirical treatment does not work in all patients. With this background present study was conducted to determine the prevalence, species distribution and antifungal susceptibility pattern of Candida species causing VVC. Material and methods: 241 vaginal swabs were collected from clinically suspected cases of VVC. Speciation and antifungal susceptibility testing (AFST) was performed using fully automated Vitek 2 compact system. Results: Prevalence of VVC in present study was found to be 12 %( 29/241). Candida albicans was the most common Candida species isolated from from.....

Keywords: Vulvovaginal candidiasis, AFST, Vitek 2 compact, automation, C.albicans, non-albicans candida

[1]. Kombade SP, Abhishek KS, Mittal P, Sharma C, Singh P, Nag VL. Antifungal profile of vulvovaginal candidiasis in sexually active females from a tertiary care hospital of Western Rajasthan. J Family Med Prim Care 2021;10:398-402.
[2]. Rati R, Patel J, Rishi S. Vulvovaginal Candidiasis and its Antifungal Susceptibility Pattern: Single centre experience. Int J Med Res Rev 2015; 3(1):72-78.
[3]. Samal R, Vaithy A, Kotasthane DS, Ghose S. Prevalence and clinico-mycological profile of vulvovaginal candidiasis in a tertiary care hospital. Int J Reprod Contracept Obstet Gynecol 2015;4:1142-7.
[4]. Esmaeilzadeh S, Omran SM, Rahmani Z. Frequency and etiology of vulvovaginal candidiasis in women referred to a gynecological center in Babol, Iran. Int J Fertil Steril 2009;3:74-7.
[5]. Nabhan A. Vulvovaginal candidiasis. Ain Shams J Obstet Gynecol 2006;3:73-8..

Abstract: Background: Pleomorphic Adenoma (PA) is a most common benign mixed tumor (50%) of major and minor salivary gland, comprising of myoepithelial and epithelial cells origin with various morphological patterns, demarcated from surrounding tissues by fibrous capsule. 40 to 70% of minor salivary gland tumors are PA's. The formation is seen in superficial lobe of lower pole of salivary gland (paratoid gland), the most common intra oral site is palate followed by upper lip and buccal mucosa. We report a patient with soft tissue swelling who is diagnosed as palate pleomorpic adenoma.

Keywords: Minor salivary glands, Pleomorphic Adenoma, Mixed tumor, Enchondroma, Palate Pleomorphic Adenoma

[1]. Luna MA, Batsakis JG, El-Naggar AK. Salivary gland tumors in children. Ann Otol Rhinol Laryngol 1991; 100:869–71.
[2]. Clauser, Luigi MD, DMD, PhD*; Mandrioli, Stefano MD*; Dallera, Vittorio MD*; Sarti, Elisabetta MD*; Galiè, Manilio MD, DMD*; Cavazzini, Luigi MD† Pleomorphic Adenoma of the Palate, Journal of Craniofacial Surgery: November 2004 - Volume 15 - Issue 6 - p 1026-1029
[3]. Byakodi S, Charanthimath S, Hiremath S, Kashalika JJ. Pleomorphic adenoma of palate: a case report. Int J Dent Case Reports. 2011; 1: 36-40.
[4]. Zemmouri Yousra et al. Pleomorphic adenoma of hard palate: a case report. Pan African Medical Journal. 2021; 38:146.
[5]. Sharma Y, Maria A, Chhabria A. Pleomorphic adenoma of the palate. Natl J Maxillofac Surg 2011; 2:169-71.

Abstract: Purpose – To study the epidemiology of cataract with laterality in elder population after covid-19 lockdown-1. Study design- A cross-sectional study Methods- Individuals more than 40 Yrs age group with cataract. The examination included visual acuity measurement, dilatation, and anterior and posterior segment examination. The lens was graded by type and severity of opacity using the Lens Opacity Classification System III (LOCS III).Main Outcome Measures -- Age, gender and laterality standardized prevalence of mature cataract and 95% confidence intervals (CIs). We defined type of cataract based on the LOCS......

Keywords: Cataract, Eye, Age

[1]. WHO. Priority eye diseases, 2010. Available at: http://www.who.int/blindness/causes/priority/en/ind ex1.html. Assessed 13 June 2015.
[2]. WHO. Universal eye health: A global action plan, 2014–2019. World Health Assembly document A66/11. 2013. Available at: www.who.int/blindness/actionplan/en/. Assessed 15 Jan, 2015.
[3]. Brian G, Taylor H. Cataract blindness - challenges for the 21st century, Bullettin of the World Health Organisation 2001;79:249-56.
[4]. Frick KD, Foster A. Magnitude and cost of global blindness: an increasing problem that can be alleviated Am J Ophthalmol. 2003;135:471-6.
[5]. Haq I, Khan Z, Khalique N, Amir A, Jilani FA, Zaidi M. Prevalence of common ocular morbidities in adult population of Aligarh. Indian J Community Medicine. 2009;34:195-201.