iosr-JDMS   Volume-22 ~ Issue-3 ~ March 2023

Abstract: Leclercia adecarboxylata has been regarded as an opportunistic pathogen that causes infections mainly in immunocompromised patients. Blood stream infections caused by L. adecarboxylata is considered as a complication in patients with indwelling catheters Although L. adecarboxylata has been recognized as a human pathogen with low virulence and high antibiotic susceptibility, there has been emergence of multi-drug resistant strains, leaving behind limited therapeutic options. We report a case of catheter-related bacteremia in a fifty-year-old female with breast carcinoma, caused by extended-spectrum beta-lactamase (ESBL) producing L. adecarboxylata. Rapid and correct identification and timely institution of appropriate antibiotic therapy was the key to favorable clinical outcome in our case.

Keywords: Leclercia adecarboxylata, Bacteremia, Indwelling catheters, ESBL

[1]. Leclerc H. Biochemical study of pigmented Enterobacteriaceae. Ann Inst Pasteur. 1962; 102:726-741. [2]. Anuradha M. Leclercia adecarboxylata isolation: case reports and review. J Clin Diagn Res. 2014; 8(12):3-4.
[3]. Stock I, Burak S, Wiedemann B. Natural antimicrobial susceptibility patterns and biochemical profiles of Leclercia adecarboxylata strains. Clin Microbiol Infect Dis. 2004;10(8):724-33.
[4]. Tamura K, Sakazaki R, Kosako Y, Yoshizaki E. Leclercia adecarboxylata gen. nov., comb. nov., formerly known as Escherichia adecarboxylata. Current Microbiology. 1986;13(4):179-84. [5]. Hess B, Burchett A, Huntington MK. Leclercia adecarboxylata in an immunocompetent patient. J Med Microbiol. 2008;57(7):896-98.
[6]. Spiegelhauer MR, Andersen PF, FrandsenTH, Nordestgaard RLM, Andersen LP. Leclercia adecarboxylata: a case report and literature review of 74 cases demonstrating its pathogenicity in immunocompromised patients. Infect. Dis. 2019;51(3):179-88.

Abstract: Any kind of waste which may be either solid or liquid containing injurious materials produced by healthcare facilities is known as biomedical waste. Management of these biomedical wastes involves separating, gathering, storing, transporting, processing and its dumping. It requires commitment at all levels from healthcare employees to sanitation workers because improper management of biomedical waste causes direct health risk to the public, the healthcare personnels and the environment. Thehealthcareprofessionalsadministrators working under public and private sector institutes, auxiliariesworking in different colleges and hospitals and various health workers of the society should be made aware of the.......

Keywords: Waste Management; Biomedical Waste; Healthcare Services; Infectious; Hazardous

[1]. Barar M, Kulkhestha A. Biomedical Waste Management: Need of Today A Review. Int J Sci and Res, 2015; 4(2): 2417-2421.
[2]. Nagpal et.al.A.Biomedical Waste Management: AReview.Heal Talk, March-April 2019,11(4): 34-36. [3]. Agrawal D, Dalal P, Srivastava JK. Biomedical Waste Management in Hospitals – A Review.Int JTechnol and Eng, 2017; 07(02): 10-16.
[4]. 4.Sharma C, Sharma RK, Prerna. A Review on Biomedical Waste Management. Int J Adv Eng and Res Dev, 2017; 4(6): 863-868.
[5]. Singh H, RehmanR,Bumb SS. Management of Biomedical Waste: A Review. Int J Dent Med Res, 2014; 1(1): 14-20.
[6]. Govt. of India, Ministry of Environment and Forests Gazette notification 2016, New Delhi.

Abstract: Background: A Delayed union is defined as a fracture which has not united in the time in which one would expect it to unite. Of the long bones, Tibia is the most common site for delayed union development. These often results in need for secondary intervention or additional treatment to stimulate bony union. Percutaneous autologous bone marrow injection is minimally invasive and can promote bone healing. PRP is autologous blood product containing very high concentration of platelets. There is currently no well established, less invasive approach available to foster fracture healing in patients with delayed unions. In view of the above facts and to find a cheap, non.....

Keywords: Delayed union, Tibia fracture, Bone Marrow Aspirate, Platelet Rich Plasma

[1]. Mandeep S Virk, Jay R Liberman. Biological adjuvants for fracture healing. Virk and Lieberman Arthritis Research & Therapy. 2012; 14:225
[2]. Evgeniya Antonova, T Kim Le, Russel Burge and John Mershon. Tibia shaft fractures: costly burden of nonunions. Antonova et al. BMC Musculoskeletal Disorders. 2013; 14:42
[3]. Katie Fong, Victoria Truong et al. Predictors of non union and reoperation in patients with fractures of the tibia: an observational study. BMC musculoskeletal Disorders. 203; 12;103.
[4]. Wang W, Yeung KWK. Bone grafts and biomaterials substitutes for bonedefect repair: a review. Bioact Mater. 2017; 2(4):224–47.
[5]. Anurabh Arora, Madan Jeyaraman. International Journal of Orthopaedic Rheumatology. 2021;7(1):53-54.

Abstract: Gene flow, genetic diversity and differentiation of myocilin gene were assessed among patients with Adult - Onset Primary OpenAngle Glaucoma in Rivers State, Nigeria. Blood samples were collected from patients and control groups from which DNA was extracted and subjected polymerase chain (PCR) using myocilin gene primers. PCR amplicons were sequenced and the sequences subjected to bioinformatics analysis. The results revealed thatnumber of segregating sites (S) was 177.00 among the control while a higher value of 194.000 was observed among the patients. Haplotype diversity (Hd) of 0.778 was observed among the control group but a higher value of 0.917 was recorded among the patients. Average number of differences (k) in the myocilin nucleotides was 36.178 among.....

Keywords: Gene flow, Genetic diversity, Glaucoma, Myocilin

[1]. Abdellaoui, R. Yahyaoui, F. and Neffati, M. (2014). Population Structure and Genetic Diversity of a Medicinal Plant Species Retama raetam in Southern Tunisia. Pakistan Journal of Biological Sciences, 17: 182-189.
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Abstract: Gun-powder fireworks are used for festivals and celebrations in most developing countries, especially in the rural areas and country-sides. Ocular injuries that are sustained throughgun-powder (cannon-gun) blastsare usually horrible and often results in structural and functional damage of the eyes and, in some cases, cause a permanent visual loss.
Here, we report a case of Mr. A.N., a 70-year-old male rural dweller in Southern Nigeria who sustained gun-powder blast injury in both eyes following careless and improper use of fireworksduring a burial ceremony. Mr. A. N. was apparently......

Keywords: Gun-powder eye injury, panophthalmitis, rural dweller, Southern Nigeria

[1]. Augsberger, J. & Asbury, T.(2008). Ocular and orbital trauma. In: Riordan-Eva P, Whitcher, J.P., editors. General Ophthalmology; 17th ed. The McGraw-Hill Companies, Inc.
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Abstract: Introduction: Relaparotomy is a laparotomy performed within 60 days of the initial surgery. Relaparotomy is a major problem for surgeons and patients as they experience second surgery within a short time period. It challenges the physical and mental endurance of patients. Aim of the study: The aim of the study was to find out the indications and risk factors of relaparotomy in gynae and obstetrics cases in DMCH. Methods: A descriptive cross-sectional study was conducted on 30 patients who met the inclusion criteria and were admitted to the Department of Gynecology and Obstetrics, Dhaka Medical College Hospitalduring the period from July 2017 to December......

Keywords: Relaparotomy, Gynecological, Obstetrics, Indications, Surgery

[1] Alam I, Mahbuba D, Das S. Relaparotomy in Obstetrics and Gynaecology Department of Faridpur Medical College Hospital - Experience in One Year. Faridpur Medical College Journal. 2013;7(2).
[2] Thombarapu U, Kodey P, Koneru G. Retrospective study of relaparotomy in department of obstetrics, gynaecology and family planning in, rural tertiary care hospital, Andhra Pradesh, India. Inte Jour of Medi Res & Health Sci. 2015;4(3):582.
[3] Rouf S, Sharmin S, Dewan F, Akhter S. Relaparotomy after Cesarean Section : Experience from a Tertiary Referral and Teaching Hospital of Bangladesh. Bangladesh Journal of Obstetrics & Gynaecology. 2010;24(1).
[4] Hasan KC, Abdul Aemmah AK. A 5-year study of re laparotomies, planned and unplanned, in Al Hillah Teaching General Hospital. Med J Babylon. 2018;15(1):25-7.
[5] Haluk RU, Erdinc K, Haldun K, Ahmet B, Mustafa P, Mehmet AO. Urgent abdominal re-explorations. World J Emerg Surg. 2006;1:10.

Abstract: Introduction: Cervical schwannomas are benign peripheral nerve tumors developed exclusively from Schwann cells. Involvement of the cervical vagus nerve is relatively rare; the treatment of these tumors is surgical. Case report: A 26-year-old patient consulted for an isolated left latero and basi-cervical mass with no adjacent inflammatory signs, evolving for four years. Imaging (CT and MRI) of the neck revealed a lateral basi-cervical left intermuscular solido-cystic mass without signs of regional infiltration, with permeable cervical vascular axes of normal caliber. A noncontributory cytological examination led to total extra capsular surgical excision of the mass by cervicotomy. It was a.....

Keywords: Schwannoma, vagus nerve, surgery.

[1]. Sinclair CF, Tellez MJ, Tapia OR, Ulkatan S, Deletis V. A novel methodology for assessing laryngeal and vagus nerve integrity in patients under general anesthesia. Clin Neurophysiol 2017;128:1399–1405.
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[3]. Bhattacharyya AK, Perrin R, Guha A. Peripheral nerve tumors: management strategies and molecular insights. J Neurooncol. 2004; 69(1–3):335-349. https://doi.org/10.1023/B:NEON.0000041891. 39474.cb
[4]. Behuria S, Rout T, Pattanayak S. Diagnosis and management of schwannomas originating from the cervical vagus nerve. Ann R Coll Surg Engl. 2015;97(2):92-97. https://doi.org/10.1308/ 003588414X14055925058355.
[5]. Câmara R, Griessenauer CJ. Anatomy of the vagus nerve. Nerves Nerve Inj. 2015;1:385-397. https://doi.org/10.1016/B978-0-12- 410390-0.00028-7.

Abstract: Introduction:Gestational diabetes mellitus (GDM) is a condition that occurs during pregnancy and is characterized by glucose intolerance. It can have severe adverse effects on fetal and neonatal outcomes. The study aimed to investigate the relationship between GDM and asymptomatic urinary tract infections among pregnant mothers. GDM affects 3-10% of pregnancies and UTIs are common in pregnant women, with around 8.3 million cases reported every year. Aim of the study: The aim of the study was toinvestigate the gestational diabetes mellitus and asymptomatic urinary tract infection among pregnant mothers.....

Keywords: Gestational, Diabetes, Asymptomatic, UTI, Pregnant

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Abstract: Introduction:Congenital heart disease (CHD) is responsible for nearly one-third of all congenital anomalies. The prevalence of CHD is 9.410 per 1000 live births, which has been increasing since 1970. The prevalence of congenital pulmonary stenosis (PS) is 8-10% (about 1 per 2000 live births worldwide) of all CHD including valvular, subvalvular, and supravalvular ones. However, this prevalence is slightly higher in Asian countries compared to Europe and the United States. PS can be present isolated or associated with other CHD, such as Ventricular Septal Defect (VSD), Patent......

Keywords: Pulmonary Stenosis, Echocardiography, PBPV, Dyspnea

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Abstract: Background:Infertility seems to be a great worldwide problem. Male infertility is a multifaceted state and overlaps a lot factors and affects infertility in about 8–5 % of the people in the world and the man is responsible for 40% of these cases. The FSH, LH and testosterone evaluation is useful in the management of male infertility. For initiation of spermatogenesis and maturation of spermatozoa, FSH is necessary. In the infertile men, higher concentration of FSH is considered to be a reliable indicator of germinal epithelial damage, and was shown to be associated with azoospermia and severe oligozoospermia Objective: The aim of the study is to analyze the levels of reproductive hormones among different groups of infertile patients........

Keywords: Infertile Male, Testosterone, Prolactin, FSH, LH, Sudanese

[1]. Bablok, L., Dziadecki, W., Szymusik, I., Wolczynski, S., Kurzawa, R., Pawelczyk, L., Jedrzejczak, P., Hanke, W., Kaminski, P. and Wielgos, M., (2011). Patterns of infertility in Poland–multicenter study. Neuroendocrinology Letters, 32(6), pp.799-804.
[2]. Connétable, D., Timoshevskii, V., Masenelli, B., Beille, J., Marcus, J., Barbara, B., Saitta, A.M., Rignanese, G.M., Mélinon, P., Yamanaka, S. and Blase, X., (2003). Superconductivity in Doped s p 3 Semiconductors: The Case of the Clathrates. Physical review letters, 91(24), p.247001.
[3]. Krester, D.M. (1979) Endocrinology of Male Infertility. Brit. Med. Bullet. 35 (2), 187-192.
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Abstract: Background:H. pylori is atype of bacterium of gram negative bacillus little pet air, that colonizes the stomach and duodenal mucosa.Mucositis is associated with the peptic ulcer in the stomach, duodenum and stomach cancer. Objective:The aim of this study is to assess the serum levels of liver function test in H. pylori patients. Materials and method:This is a cross sectional study, conducted in Port Sudan, Red Sea State, Sudan, during the period from July to October 2019. Include one hundred samples, 50 H.pylori infected patients were selected as study group and....

Keywords: Liver Function Tests, H. pylori Infection

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[2]. Figura, N., Franceschi, F., Santucci, A., Bernardini, G., Gasbarrini, G. and Gasbarrini, A., (2010). Extragastric manifestations of Helicobacter pylori infection. Helicobacter, 15, pp.60-68.
[3]. Bulajic, M., Panic, N., Stimec, B., Isaksson, B., Jesenofsky, R., Schneider-Brachert, W. and Löhr, J.M., (2012). PCR in Helicobacter spp. diagnostic in extragastric malignancies of digestive system. European journal of gastroenterology &hepatology, 24(2), pp.117-125.
[4]. Huang, Y., Tian, X.F., Fan, X.G., Fu, C.Y. and Zhu, C., (2009). The pathological effect of Helicobacter pylori infection on liver tissues in mice. Clinical microbiology and infection, 15(9), pp.843-849.
[5]. Goo, M.J., Ki, M.R., Lee, H.R., Yang, H.J., Yuan, D.W., Hong, I.H., Park, J.K., Hong, K.S., Han, J.Y., Hwang, O.K. and Kim, D.H., (2009). Helicobacter pylori promotes hepatic fibrosis in the animal model. Laboratory investigation, 89(11), pp.1291-1303

Abstract: Congenital pouch colon is a very rare abnormality in which varying degree of pouch-like dilatation of dysplastic colon is associated with an anorectal malformation. The pouch usually communicate with a fistulous track with the genitourinary tract. CPC is classified on anatomic morphology into five types as per the length of the colon involved. In "Saxena and mathur Classification based on anatomic morphology the type 5 CPC shows double ouch colon with short normal interpositioned colon segment. CPC malformation is exclusively seen in Northern India, only (7.8%) cases of (CPC) have been reported outside India. However, recently there is increasing awareness about this rare anomaly and some cases are now reported from other parts of the world. The aim....

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