iosr-JDMS   Volume-20 ~ Issue-1 ~ January 2021

Abstract: Background : Malaria one of the most complex infectious disease with varied type of clinical presentation and challenge for treatment. In this study few cases with plasmodium falciparum malaria infection are showing Biochemical subclinical hypothyroidism and overt hypothyroidism .Studies of these cases with complete blood count and peripheral smear provide an opportunity to visualise various stages of Malarial parasites infecting RBC and concurrent examination with T3,T4 and TSH provide to know the function of thyroid gland. This Article was written to evaluate the patients with subclinical hypothyroidism for Plasmodium falciparum malaria. Rigorous treatment for plasmodium falciparum malaria parasite may prevent cases from associated morbidity like hypothyroidism. Since there were no studies comparing malarial parasites seen in peripheral smear and biochemical changes in thyroid...

Key Words : Fever; Anaemia; Thrombocytopenia; Plasmodium Falciparum Malaria; Thyroid Stimulating Hormone; Subclinical Hypothyroidism; Overt Hypothyroidism

[1]. Vaheb Fatourechi. MD. Subclinical hypothyroidism: An update for Primary care physicians Mayo clin Proc. 2009 Jan; 84(1) : 65-71. [PMCID:PMC 2664572] [PMID 19121255]. https://www.ncbi.nim.nih/gov/pmc/articles/PMC2664572.
[2]. Bernadette Biondi, MD1; Anne R. Cappola, MD, ScM2, 3; David S. Cooper, MD4. Subclinical hypothyroidism A Review. JAMA .2019;322(2):153-160.doi:10.1001/jama.2019.9052.https://JAMANETWORK.COM/JOURNALS/JAMA/ARTICLE-ABSTRACT/2737687.
[3]. Reyburn H, Mbatia R, Drakeley C, Carneiro I, Mwakasungula E, Mwerinde O, Saganda K, Shao J, Kitua A, Olomi R, Green-wood BM,Whitty CJ. Over diagnosis of malaria in patients with severe febrile illness in Tanzania: a prospective study. BMJ.2004; 329:1212-1217 [PMC Free Article] [PUBMED] [Google Scholar]
[4]. Mwangi TW, Ross A, Snow RW, Marsh K. Case definitions of clinical malaria under different transmission conditions in kilifi District, Kenya J Infect Dis. 2005;191:1932-1939 [PMC Free article] [PUBMED] [Google Scholar]
[5]. Cooper DS. Subclinical hypothyroidism. N Engl J Med.2001;345(4):260-265 [PUBMED] [Google Scholar]..

Abstract: RESUME : Liposarcome est une tumeur mésenchymateuse , primitive, maligne et rare . La localisation retro péritonéal représente 12 a 15% des sarcomes des tissus mous. Nous rapportons l'observation d'un homme âgé de 48 ans , qui a bénéficié le mois du juillet 2020 ( pendant la période de la pandémie COVID 19 ) d'une exérèse complète d'un liposarcome a double composante bien différenciées et pléomorphe de 24 centimètres ENGLISH ABSTRACT : Liposarcoma is a rare and primary malignancy developed from mesenchymal tissu. The retroperitoneal location represents 12 a 15 % of the soft tissue sarcomas......

Key Word: Liposarcoma , retroperitoneal location , covid 19 pandemic

[1]. Antinori A, Antonacci V, Magistrelli P. Giant retroperitoneal liposarcoma. Am J Surg 2002;184(1):56–7
[2]. Lachachi F, Antarieu S, Valleix D, Decottes B. Liposarcome rétropéritonéal volumineux, à propos d'un cas et revue de la littérature. J Chir 1995;132:309–13
[3]. Karanikas I, Liakakos T, Koundowakis S, Papadopolos A, Garsallah M, Dendrinos S. Surgical management of primary retroperitoneal liposarcoma. Acta Chir Belg 1993;93:177–80.
[4]. Hagege H, damasio-Colombo M, Fouet P. Les liposarcomes rétropéritonéaux : mise au point à propos de deux observations. Sem Hôp Paris 1987;63:1181–5
[5]. Stoeckle E, Ciondre JM, Bonvalot S, Kantor G, Terrier P, Bonichon F, et al. Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group. Cancer 2001;92(2):359–68..

Abstract: Objectives- Sarcomas of head and neck (HN) are rare malignant tumors of mesenchymal origin which account 1% of all HN malignancies. The objective was to review the literature to emphasize on classification, aetiology, diagnosis and staging, various treatment modalities and recent updates on HN sarcomas. Method- An electronic data search was done in April 2020 without any time-bound factor on "PubMed," National Library of Medicine, the National Institute of Health, "Science Direct," and "Web of Science" databases. Keywords searched were "head and neck sarcomas" AND "osteosarcoma" AND "Ewing's sarcoma" AND "chondrosarcoma" AND "malignant fibrous histiocytoma" AND "fibrosarcoma" AND "Liposarcoma" AND "rhabdomyosarcoma......

Key Word: 'sarcoma', 'head and neck sarcoma', 'soft tissue sarcoma','radiation induced sarcoma', 'osteosarcoma', 'chondrosarcoma'

[1]. NCI Search Results - National Cancer Institute. (2011). https://www.cancer.gov/search/results September 5, 2020.
[2]. Brockstein B. Management of sarcomas of the head and neck. Curr Oncol Rep. 2004 Jul;6(4):321–7.
[3]. Peltier LF. Historical note on bone and soft tissue sarcoma. J Surg Oncol. 1985 Dec;30(4):201–5.
[4]. Fletcher CDM, Unni KK, Mertens F, Weltgesundheitsorganisation, Pathology and genetics of tumours of soft tissue and bone ; Lyon: IARC Press; 2002.
[5]. Jo VY, Fletcher CDM. WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition. Pathology (Phila). 2014 .

Abstract: Background: Urinary stone disease has afflicted mankind for a long. The technical advancements in urology have profoundly changed the management of upper ureteric calculus. The aim of this study to comparing short-term clinical outcomes of Antegrade percutaneous ureterolithotripsy (APCUL) with Retrograde ureterolithotripsy (URSL) in the management of impacted upper ureteric stone patients and the feasibility of undertaking this in HUSM. This study also analyzed the local data, which reflected our performance and achievement in our Centre to the patients. Material and methods: Our inclusion.......

Key Word: Upper ureteric stone, Antegrade Percutanenous ureterolithotripsy, Retrograde ureterolithotripsy

[1]. Hussain M, Ali B, Ahmed S, et al. Prediction of renal function recovery in obstructive renal failure due to stones. J Pak Med Assoc 1997;47:159–61.
[2]. Wolf JS Jr. Treatment selection and outcomes: Ureteral calculi. Urol Clin North Am 2007;34:421‐30.
[3]. Morgentaler A, Bridge SS, Dretler SP. Management of the impacted ureteral calculus. J Urol 1990;143:263‐6.
[4]. Lopes Neto AC, Korkes F, Silva JL 2nd, Amarante RD, Mattos MH, Tobias‐Machado M, et al. Prospective randomized study of large proximal treatment ureteral stones: Extracorporeal shock wave lithotripsy versus ureterolithotripsy versus laparoscopy. J Urol 2012;187:164‐8
[5]. Mugiya S, Ozono S, Nagata M, et al. Retrograde endoscopic management of ureteral stones more than 2 cm in size. Urology 2006;67:1164–8.

Abstract: Scrub typhus, a zoonosis caused by bacterium Orientia tsutsugamushi. Commonly manifest as acute febrile illness, however atypical presentation with resultant delay in diagnosis and treatment may occur. Multi-organ failure with high mortality in such cases is major concern while dealing with this common disease. Here we are reporting an interesting case of scrub typhus presenting as acute mastoiditis.

Key Word: Scrub typhus, acute mastoiditis, zoonosis, eschar, Orientia tsutsugamushi.

[1]. Walker DH, Dumler JS, Marrie T. Rickettsial Diseases. (Part 8,Section 10, Chapter 174) In: Longo DL, Fauci AS Kasper DL,Hauser SL, Jameson JL, Loscalzo J, editors. Harrison's Principle of Internal Medicine. 18th ed. USA: The McGraw‑Hill Companies; 2012. p.1064‑5.
[2]. Rapsang AG, Bhattacharyya P. Scrub typhus. Indian J Anaesth 2013;57:127-34.
[3]. Chang WH. Current status of tsutsugamushi disease in Korea. J Korean Med Sci 1995;10:227‑38.
[4]. Mahajan SK, Kashyap R, Kanga A, Sharma V, Prasher BS, Pal LS. Relevance of Weil‑Felix test in diagnosis of scrub typhus in India. J Assoc Physicians India 2006;54:619‑21.
[5]. Devine J. A review of scrub typhus management in 2000-2001 and implications for soldiers. Journal of Rural and Remote Environmental Health. 2003;2(1):14- 20.

Abstract: Globally 8–12% of couples experience difficulty conceiving a child. 1This study was conducted to checkwhether sexual dysfunction ismore in infertile males in relation to normal healthy men through comparingsexual aspects& frequency of sexual problems in both groups. The secondary objective was: to determine factors affecting occurrence of male sexual dysfunction. Infertility has been described as a stressor and a life crisis for individuals or couples, which results in a lower quality of life and marital conflicts. 2,3 there are many factors which affect the sexual performance other than fertility status like erectile problems, premature ejaculation, lack of pleasurable activity or inability to complete activity to a point of orgasm. In our study we found that infertile men with younger age group.

Key Word: Sexual dysfunction, Infertile men, fertile men.

[1]. World Health Organization. Recent Advances in Medically Assisted Conception. WHO Technical Report Series 820. Geneva: World Health Organization Publications 1992;1-7.
[2]. Monga M, Alexandrescu B, Katz SE, Stein M, Ganiats T. Impact of infertility on quality of life, marital adjustment, and sexual function. Urology 2004;63(1):126-30.
[3]. Klemetti R, Raitanen J, Sihvo S, Saarni S, Koponen P. Infertility, mental disorders and well-being – a nationwide survey. ActaObstetGynecolScand 2010;89(5):677-82.
[4]. Shindel AW, Nelson CJ, Naughton CK, Ohebshalom M, Mulhall JP. Sexual function and quality of life in the male partner of infertile couples: prevalence and correlates of dysfunction. J Urol 2008; 179 (3): 1056-9. doi: 10.1016/j.juro. 2007.10.
[5]. Drosdzol A, Skrzypulec V. Quality of life and sexual functioning of Polish infertile couples. Eur J ContraceptReprod Health Care 2008; 13 (3): 271-81.

Abstract: Objective: To apply the M-CHAT questionnaire (Modified Checklist for Autism in Toddlers) to children diagnosed with food allergy, analyzing the prevalence of symptoms of autism in children with food allergy. Methods: Descriptive, exploratory and cross-sectional study conducted by applying the M-CHAT questionnaire to the guardians of children aged 16 months to 4 old-years, diagnosed with food allergy, who has received special diet at municipal specialized out-patient clinicin care of these children, from April/2019 to July/2020. The selection of voluntary participants was by convenience and Parental Written Informed Consent form were obtained for subsequent completion of the M-CHAT, in addition to this, thevariables sex and age were analyzed, further the statistical analysis of the results........

Key Word: autism spectrum disorder, food allergy, child, gut microbiome

[1]. Portes JRM, Vieira ML, Souza CD, Kaszubowski E. Estilos parentais e coparentalidade em famílias com crianças com autismo: análise de agrupamento do comportamento das crianças. Estud. Psicol. 2020; (37): 1-12.
[2]. Bölte S, Girdler S, Marschik PB. A contribuição da exposição ambiental para a etiologia do transtorno do espectro do autismo. Ciências da Vida Celular e Molecular. 2019; (76): 1275-1297.
[3]. Kerins MR. Child and Adolescent Communication Disorders-Organic and Neurogenic Bases. San Diego CA:Plural Publishing, 2015. 457 pp. ISBN 978-1-59756-656-8. Disponível em <http://dx.doi.org/10.1044/policy.GL2006-00049>. Acessoem 10 jan.de 2020.
[4]. Goines P, Van de Water J. The immune system's role in the biology of autism. Cur Op Neurol. 2010;23(2):111–117.
[5]. Zerbo O, Leong A, Barcellos L, Bernal P, Fireman B, Croen LA. Immune Mediated Conditions in Autism Spectrum Disorders. Brain Behav Immun. 2015;46:232–236.

Abstract: AIM: To study the effect of Blunt Injury Abdomen and their impact on abdominal viscerae and various associated injury in Blunt Injury Abdomen and to correlate the findings of abdominal sonography in trauma with laparotomy findings. METHODS: Thirty four cases of blunt abdominal trauma admitted at Government Mohan Kumaramangalam Medical College and Hospital during the period of December 2018 to November 2019 were taken for this study. The cases were selected in such a way that only those patients with definitive history and clinical findings suggestive of injury to Viscerae which were later confirmed by investigations, laparotomy and autopsy. The clinical features were studies in details with special note to any associated injuries like head injury, chest injury and fracture limbs........

[1]. Sabistan D C Text book of surgery.
[2]. Campbell's Text book of urology. 6th edition. Genitourinary trauma
[3]. American College of Surgeons Committee on Trauma. Abdominal Trauma. In: ATLS Student Course Manual. 8th. American College of Surgeons; 2008.
[4]. Maingot's Abdominal operations 10th edition – Blunt abdominal trauma
[5]. Enderson BL, Reath DB, Meadors J, Dallas W, DeBoo JM, Maull KI. The tertiary trauma survey: a prospective study of missed injury. J Trauma. Jun 1990;30(6):666-9; discussion 669-70.

Abstract:AIM: To determine Incidence, Age and Sex Incidence and to evaluate various clinical parameters of both uncomplicated and complicated Liver Abscess and various modalities of treatment available and to know prevalence occurring as abdominal emergencies METHODS: The materials used in the study consisted of 80 cases of liver abscess which were admitted in all surgical wards of Government Mohan Kumaramangalam Medical College and Hospital, Salem during January 2019 – January 2020. RESULTS: Males are most commonly affected with Liver Abscess and 40-50 years is the most commonly affected age group. Most of the Liver Abscess presented with Right Upper Quadrant pain without peritonitis. Single Right Lobe Liver Abscess id the predominant presentation. E.Coli is the most commonly associated organism and majority of the patients underwent aspiration successfully..........

[1]. Sir Alfred Cuschieri, Rober J.C. Steele, Abdool Rahim Moosaa - Essential Surgical Practice 4th Edition
[2]. Sabiston textbook of surgery Vol-2, 18th Edition.
[3]. Chummy S. Sinnatamby – Last's Anatomy Regional and applied 10th Edition.
[4]. Oxford Text Book of Surgery Peter. J. Morris and Ronal A. Malt First Edition.
[5]. Chatterjee K.D., Parasitology 12th Edition.
[6]. Maingot's Abdominal Operations 10th Edition

Abstract: Background: COVID-19 is fast spreading not only across country borders but is seen to involve all ages and walks of life. The risk of acquiring the infection is considered to be high especially among the health care givers. The study is to look into the characteristic profile and clinical outcome in the infected Health care workers (HCWs). Method: An observational study was conducted in a cohort of HCWs actively involved in patient care at a tertiary hospital in Northeast India. Results: There were 115 cases of health care workers infected with COVID-19 in our institute over a span of 9 months from March 2020 to November 2020. Among them 59 were doctors, 32 were nurses, 9 were technicians and 15 were orderlies. The median age of our HCWs.......

Key Word: COVID-19 infection, health care workers, Hydroxychloroquine prophylaxis, Northeast India

[1]. GuoYR, Cao QD, Hong ZS, Tan YY, Chen SD, Jin HJ, Tan KS, Wang DY, Yan Y (2020) The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak—an update on the status. Mil Med Res 7(1):11. [2]. H, Stratton CW, Tang YW. Outbreak of Pneumonia of Unknown Etiology in Wuhan China: the Mystery and the Miracle. J Med Virol 2020; published online 16 January. doi:10.1002/jmv.25678. [3]. Yogesh G.Dabholkar, Bhagyashree Ajit Sagane, T.Y Dabholkar et al. COVID19 infection in Health care professionals: Risks,Work-safety and psychological issues. Indian J Otolaryngol Head Neck Surg Oct- Dec 2020 72 (4);468-473 [4]. Indian Council for Medical Research. Recommendation for Empiric use of Hydroxychloroquine for Prophylaxis of SARS-CoV-2 Infection. Available from: https://icmr.nic.in/sites/default/files/upload_docum ents/HCQ_Recommendation_22March_final_MM_V2.pdf.

Abstract: Background: Chronic suppurative otitis media (CSOM) is one of the common infective conditions which can cause many complications if not treated properly. Improper use of antibiotic among the common population has led to many drug resistant organisms, therefore it is necessary to study the antibiotic susceptibility pattern before treating the patient with CSOM. Aim of the study was to identify the bacterial isolates causing CSOM and to study their antibiotic susceptibility pattern after an empirical treatment. Materials and Methods: This study was undertaken in a tertiary care center of Ahmedabad, Gujarat with an aim to study the bacterial flora and their sensitivity to a series of antibiotics in cases of CSOM with purulent discharge after an empirical treatment.........

Key Word: Ear discharge , chronic suppurative otitis media , antibiotic sensitivity, empirical treatment.

[1]. Healy GB, Roshe KW. Otitis media and middle ear effusions. In: Snow, Ballenger JJ, editors. Ballenger's otorhinolaryngology Head Neck Surgery. 16th Ed. BC Decker Inc; 2005: 249-260.
[2]. Shenoi PM. Management of chronic suppurative otitis media. Scott Brown's textbook of Otorhinolaryngology. 8th Edition. 2018;2:215.
[3]. Fliss DM, Shoham I, Leiberman A, Dagan R. Chronic suppurative otitis media without cholesteatoma in children in southern Israel: incidence and risk factors. Paediatric Infec Dis J. 1991;10:895-9.
[4]. Acuin J. World Health Organization. Chronic suppurative otitis media: Burden of illness and management options. Geneva, Switzerland: World Health Organization; 2004.
[5]. Haynes DS. Perioperative antibiotics in chronic suppurative otitis media. Ear Nose Throat J. 2002;81:13-5.

Abstract: Background: Hypertensive disorders represent one of the most common medical complications of pregnancy. Based on a nationwide inpatient sample examining more than 36 million deliveries in the United States, the prevalence of associated hypertensive disorders increased from 67.2 per 1,000 deliveries in 1998 to 83.4 per 1,000 deliveries in 2006. Women who develop severe hypertension during pregnancy may experience adverse effects similar to those associated with mild preeclampsia. Materials and Methods: In this Prospective Analytical hospital based study, 35 patients in group 1 and 70 patients in group 2 were included. Booked pregnant females with already diagnosed gestational hypertension on treatment or newly diagnosed gestational hypertension at 34 weeks.......

Key Word: Gestational Hypertension; BMI; Induction; Antepartum; Intrapartum; Postpartum; NICU.

[1]. Roccella EJ. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. American Journal of Obstetrics & Gynecology. 2000;183(1):S1–S22
[2]. Report of the National High Blood Pressure Education Program Working Group on high blood pressure in pregnancy. Am J Obstet Gynecol. 2000;183(1):S1-S22.
[3]. Sibai BM. Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol. 2003;102(1):181-192.
[4]. Kuklina EV, Ayala C, Callaghan WM. Hypertensive disorders and severe obstetric morbidity in the United States. Obstet Gynecol. 2009; 113(6):1299-1306.
[5]. Villar J, Carroli, G, Wojdyla D, et al; World Health Organization Antenatal Care Trial Research Group. Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions. Am J Obstet Gynecol. 2006;194(4):921-931.