iosr-JDMS   Volume-18 ~ Issue-4 ~ April-2019

Abstract: Disease of maxillary anterior teeth resulting from any injury is a relatively common event. These teeth should be properly managed to improve long term success rate and better prognosis. Recently in many literature Mineral trioxide aggregate(MTA) has emerged as a biocompatible material that stimulate peri-radicular tissue repair at the root end region. In this article, we present a case report of management of big cystic lesion in relation to the apex of the maxillary anterior teeth. Root canal treatment was followed by resection of root end of tooth at the apex level and sealed with Mineral trioxide aggregate(MTA). Ten month follow up , both clinically and radiograph shows excellent prognosis

Keywords: root canal therapy, apicoectomy, periapicl cyst, ,periapicalobturation, Mineral trioxide aggregate(MTA)

[1]. George Bogen, Sergio Kuttler. Mineral Trioxide Aggregate Obturation: A Review and Case Series. JOE-2009, Vol. 35, No. 6.
[2]. AdityaShetty, C. Ravi Chandra, Mithra N. Hedge, Uday S. Mahale, Ganesh Bhat. Mineral Tri-oxide Aggregate (MTA) For The Repair Of Periapical Tissues In A Patient With Self Inflicted Injuries: Case Report. NUJHS 2013, Vol. 3, No 1; 86-89.
[3]. Seung-Ho Baek, Woo Cheol Lee, Frank C. Setzer, Syngcuk Kim. Periapical Bone Regeneration after Endodontic Microsurgery with Three Different Root-end Filling Materials: Amalgam, SuperEBA, and Mineral Trioxide Aggregate. JOE-2010, volume 36, Number 8; 1323-1325.
[4]. Dr Mohammed Sadique, DrNithu Marina Terence, Dr B Bhavya, Dr Benny Varghese. Surgical Management of A Large Periapical Lesion with Prf And Xenograft- A Case Report. IOSR-JDMS, 2016, Volume 15, Issue 5 Ver. VI; 1-3.
[5]. Casper Kruse, Rubens Spin-Neto, Rene´ Christiansen, Ann Wenzel, Lise-LotteKirkevang. Periapical Bone Healing after Apicectomy with and without Retrograde Root Filling with Mineral Trioxide Aggregate: A 6-year Follow-up of a Randomized Controlled Trial. J Endod 2016; 1-5..

Abstract: Asthma is a common respiratory disease characterised by chronic inflammation of airways leading to reversible airway obstruction. Inhalation therapy forms the mainstay of treatment of asthma. Inhaled medications are available in various dispensers which includes metered dose inhaler, dry powder inhaler, nebulizers etc. Adherence to inhalation therapy has direct relationship to the treatment outcome of asthma and it requires proper understanding by the patientabout the modality of treatment they receive. Various patient related factors has shown to affect the........

Key Words: Asthma, Inhaler, Knowledge, Attitude, Practice

[1]. Meza C, Gershwin E. Why is asthma becoming more of a problem? Pulm Med 1997;3:6-9.
[2]. National Asthma Education and Prevention Program, National Heart, Lung, and Blood Institute: Expert Panel Report 2: Guidelines forthe Diagnosis and Management of Asthma, National Institutes of Health Publication No. 97-4051, Bethesda, MD, NHLBI, 1997.
[3]. Demiralay R. Comparison of the effects of three forms of individualized education on asthma knowledge in asthmatic patients. Turk J Med Sci 2002;32:57-64

[4]. Klein JJ, van der Palen J, Uil SM, Zielhuis GA, Seydel ER, Van Herwaarden CL. Benefit from the inclusion of self-treatment guidelines to a self-management programme for adults with asthma. EurRespir J 2001;17:386-94.
[5]. Anjankumar DS, Adepu R, Parthasarathi G, Mahesh PA. Impact of Community Pharmacist Provided Patient Education in Asthma patients on Treatment Outcomes-A study. Indian J Pharm Educ Res 2009;43(2):125-33..

Abstract: Context: Taxane (Paclitaxel and docetaxel) are microtubule inhibitors, extensively used for breast carcinoma. Chemotherapy induced peripheral neuropathy not only leads to discomfort but the severity of neuropathy leads to disability resulting in significant loss of body functions, compromising the Quality of life (QOL) of patients. Objective: The aim of the study is to evaluate the severity of symptomatic TIPN and corroborating it with patients QOL. Material and Methods: 31 newly diagnosed cancer patients were selected scheduled to be treated with taxane monotherapy with 3 weekly regimens for 6 cycles with standard dosage (175-200mg/m2). Evaluation was done in 3 phases, i.e., before, after 3rd......

Key Words: Taxane, Peripheral neuropathy, Quality of Life, Total neuropathy score.

[1]. WHO news. https://www.who.int/newsroom/factsheets/detail/cancer
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Abstract: Background- Chronic Hepatitis B is an important global health problem, with more than 350 million individuals affected worldwide. Its prevalence in india and many other parts of the Asia pacific region is quite high. More than 10,00,000 indian children run a lifetime risk of becoming chronic barriers and about 1,00,000 indians die from HBV complications annually. A decision analytical model estimates that in India, vaccination would save 25 lives per 1lakh population per year. Hence the present study has been conducted to know the awareness of nurses about this disease as they constitute people at major risk for HBV infection. Materials and methods:Type of study: Cross sectional descriptive observational study. Duration: 1 month 15 days.[AUGUST 1s -SEPTEMBER 15th 2017] Study population: Nursing staff of GGH, Vijayawada.Study instrument: A.......

[1]. world health organization. global hepatitis report ,2017.www.who.int/mediacentre/factsheets/fs204/en/
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[4]. Imam SF, Haroon M, Amir R. Status of immunization against Hepatitis-B virus infection among healthcareworkers. Biomedical 2000;16:25-7.
[5]. Amanpreet Kaur et al. Awareness, Attitude and Vaccination Status Regarding Hepatitis B among Staff Nurses of a Teaching Hospital in North India.OHDM - Vol. 15 - No.4 - August, 2016..

Abstract: Introduction: Long standing duodenal perforation presenting as retroperitoneal abscess. Case Report: We report a case of 60 year old female of sealed duodenal perforation presenting as retroperitoneal abscess. CECT abdomen revealed abscess in paraduodenal, paraaortic and paracolic gutter. On pus culture it came out to be E. Coli positive. Endoscopy revealed healing ulcer in posterior duodenal wall. Patient was treated conservatively using percutaneous drainage and IV antibiotics. Conclusion: Any reteroperitoneal abscess of unknown origin should include CECT and upper GI endoscopy to rule out duodenal perforation as its cause.

Key Words: duodenal perforation, reteroperitoneal abscess.

[1]. Bell RL, Seymour NE. Abdominal wall, omentum, mesentery, and retroperitoneum. Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Hunter JG, Pollock RE, editors. In Schwartz's Manual of Surgery. 8thed. The McGraw-Hill Companies; 2006. p. 897-905.
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Abstract: Tissue inhibitor of metalloproteinases-1 (TIMP-1)is involved in extracellular matrix remodeling whichis considered to be a marker of regulation of matrix metalloproteinase activity. Methods– An enzyme-linked immunosorbent assay prior to a radiofrequency catheter ablation (RFA) procedure was used for measuring the serum level of TIMP-1 in 210 patients: 80 patients without history of atrial fibrillation (AF) and 80 patients with idiopathic AF (paroxysmal AF – 30, persistent AF – 32, long-standing AF – 35 and permanent AF – 33). Their relationship with intraoperative efficacy and recurrence of AF was evaluated throughout the observation period........

Key Words: TIMP-1, fibrillation, ablation, matrix

[1]. Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, Gillum RF, Kim YH, McAnulty JH Jr, Zheng ZJ, Forouzanfar MH, Naghavi M, Mensah GA, Ezzati M, Murray CJ. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation 2014; 129:837–847.
[2]. Laila Staerk, Jason A. Sherer, DaraeKo, Emelia J. Benjamin, Robert H. Helm Atrial Fibrillation Epidemiology, Pathophysiology, and Clinical Outcomes. Circulation 2017; 120:1501-1517.
[3]. Pappone C, Vicedomini G, Augello G, Manguso F, Saviano M, Baldi M, et al. Radiofrequency catheter ablation and antiarrhythmic drug therapy: a prospective, randomized, 4-year follow-up trial: the APAF study. CircArrhythmElectrophysiol. 2011;4(6):808-14.
[4]. Elayi CS, Verma A, Di Biase L, Ching CK, Patel D, Barrett C, et al. Ablation for longstanding permanent atrial fibrillation: results from a randomized study comparing three different strategies. Heart Rhythm. 2008;5(12):1658-64.
[5]. Calkins H, Kuck KH, Cappato R, Brugada J, Camm AJ, Chen SA, et al. 2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. Europace. 2012;14(4): 528-606.

Abstract: Non-communicable diseases are silent killers and it is one of the four mortality rate from other conditions. Communities are striving to cease up the problem via engaging in physical exercise; and on the other continuum persons struggle to advance their life style. Thus, physical exercise should be accustomed by the individual if not prohibited by health conditions of the person; however the physiological and cognitive health is affected by non-communicable diseases; type 2 diabetes mellitus and hypertension. The intent of this paper was to compare the exercise prescriptions for type 2 diabetes mellitus and hypertension in Hawassa town Hospitals and gymnasiums. To manipulate......

Key Words: type 2 diabetes mellitus, hypertension, exercise prescription

[1]. Moscatiello, S., Manini, R., Marzocchi, R., and Marchesini, G. (2007). Role of Physical Exercise
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[4]. Vilberto, S. (2007). Molecular Modifications Induced by Physical Exercise: A Significant Role in Disease Prevention. Arti Grafiche Nidasio, Assago, Milan, Italy. Springer-Verlag Italia S.r.l., Via Decembrio 28, I-20137 Milan, Italy.
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Abstract: In current scenario, Diabetes (Hyperglycemia) is a major health problem in the middle and old aged populationworldwide. It affects Micro as well as Macrovascular arrangement of the diabetic patients. Microvascular complications are most serious life condition in which Microvascular ocular complications are sight threatening. Many other ocular complications are seen in peoples with diabetes.The aim of study was to "Calculate prevalence of various types of ocular complications in diabetic peoples". Total 887 diabetic peoples (irrespective of type, duration and medication of diabetes), were included in this cross-sectional study. No age limitation was taken in this study. Proper......

[1]. Diabetes Fact Sheet, WHO, November 2008. (http://www.who.int/mediacentre/factsheets/fs312/en/).
[2]. V. Usuelli and E. La Rocca, "Novel therapeutic approaches for diabetic nephropathy and retinopathy," Pharmacological Research, vol. 98, pp. 39–44, 2015.
[3]. F. Semeraro, A. Cancarini, R. dell'Omo, S. Rezzola, M. R.Romano, and C. Costagliola, "Diabetic retinopathy: vascular and inflammatory disease," Journal of Diabetes Research, vol. 2015, Article ID 582060, 16 pages, 2015.
[4]. D. Gologorsky, A. Thanos, and D. Vavvas, "Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy," Mediators of Inflammation, vol. 2012, Article ID 629452, 10 pages, 2012.
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Abstract: The aim of the study was to analyze the results of fixation of supracondylar fractures by open vs. closed reduction followed by internal fixation with k wires and assessing the union radiologically, complications associated with the procedure and restoration of range of motion and function of the elbow and to evaluate the results clinically regarding pain, stiffness, range of motion. our study was conducted on 15 pt who attended orthopaedics opd /emergency rimsh with extension type of supracondylar fracture (gartland ii & iii).closed manipulation was done with application of posterior POP slab for immobilization. Check X ray was done .on adequate reduction pt was sent back home .Inadequate reduction were admitted and was planned for OT either percutaneous pinning or ORIF with k wire. Study subject were divided into 2groups .group I = closed reduction with percutaneous.......

Key Words: children, closed pinning, open fixation, supracondyler fracture

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[4]. Pirone AM, Graham HK, Krajbich JI. Management of displaced extension-type supracondylar fractures of the humerus in children. J Bone Joint Surg Am ,70(5),1988:641–50.
[5]. Reitman RD, Waters P, Millis M. Open reduction and internal fixation for supracondylar humerus fractures in children. J PediatrOrthop ;21(2),2001:157–161..

Abstract: Introduction: Seizure duration at electroconvulsive therapy (ECT) has been a focus of clinical and research attention for decades. Seizure duration is monitored at every ECT session and is used as reference for stimulus dosage adjustment. The current retrospective analysis focuses on the relationships between seizure duration and seizure threshold at ECT and impact of duration of illness in both old and new cases. Aim: The aim of the study is to assess the relation between seizure threshold , duration of seizure and duration of illness. Methods: This is a retrospective study conducted at Government Hospital for Mental care, Visakhapatnam. The sample includes 60 subjects.......

Key Words: Electroconvulsive therapy, Seizure threshold, Seizure duration

[1]. Maletzky BM. Seizure duration and clinical effect in electroconvulsive therapy..Compr. Psychiatry 1978; 19: 541– 580.
[2]. Royal College of Psychiatrists. The ECT Handbook. the 2nd Report of the Royal College of Psychiatrists' Special Committee on ECT. Council Report CR39. Royal College of Psychiatrists, London, 1995.
[3]. Abrams R. Electroconvulsive Therapy, 3rd edn. Oxford University Press, New York, 1997.
[4]. American Psychiatric Association. The Practice of ECT. Recommendations for Treatment, Training and Privileging. American Psychiatric Association, Washington DC, 1990.
[5]. Sackeim HA, Devanand DP, PrudicJ.Stimulus intensity, seizure threshold, and seizure duration: Impact on the efficacy and safety of electroconvulsive therapy..Psych. Clin. North Am. 1991; 14: 803 – 843..

Abstract: Background: Neonatal seizure does not constitute a diagnosis but is a manifestation of an underlying disease of the central nervous system which may be due to systemic and biochemical disturbances. A study was conducted on neonates with seizures for a period of 1 year from 1st August 2016 to 31st July, 2017 Objective: To determine the biochemical abnormalities in neonatal seizures Design: Prospective cross-sectional hospital based study Setting: NICU of Gauhati Medical College and Hospital Methods: A prospective cross-sectional hospital......

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[2]. Singh M. Neurology disorders. In: Singh M, eds. Textbook of Care of Newborn. 8th ed. (Delhi: CBS Publication; 2017) 437-444.
[3]. Vigavano F. Benign familial infantile seizures. Brain Dev. 2005;27:172.
[4]. Bergin AM. Neonatal Seizures. In: Cloherty JP, Eichenwald EC,Hansen AR, Stark AR (eds). Manual of Neonatal Care. 7 ed. (Lippincott Williams & Wilkins, Philadelphia; 2012) 729-42.
[5]. Cockburn F, Brown JK, Belton NR, Forfar JO. Neonatal convulsions associated with primary disturbance of calcium, phosphorus and magnesium metabolism. Arch Dis Child 1973;48: 99-108..

Abstract: In a developing country like India, the estimated annual burn incidence is approximately 6-7 million every year. The high incidence is attributed to illiteracy, poverty and low level of safety consciousness in the population at large. The incidence of upper extremity burns constitutes a major chunk amongst them. In addition to physical disabilities the burn patients suffer psychologically and are unable to take, their proper place in the society. The non -utilization of their abilities is loss to the family, community and country. Help from any conceivable quarter for their.......

[1]. Burns, national health portal, sep o6,2016
[2]. Avni T, Levcovich A, Ad-El DD, et al. Prophylactic antibiotics for burn patients: Systemic review and analysis: Br med J. 2010; 340: c241.
[3]. Pocter F: Rehabilitation of the burn patient. Indian J.Plastic surg 2010, 43: 101- 13.
[4]. Edgar D: Active burn rehabilitation starts at the time of injury: An Australian perspective. J Bum Care Res,2009:30:367-82.
[5]. Atiyeh BS, Costagliola m, Hayek SN Burn prevention mechanism and outcomes: pitfalls, failures and successes. Burns 2009,35:181-93...

Abstract: PRF is a second-generation platelet concentrate and can be distinguished in P-PRF (Pure Platelet-rich fibrin) and L-PRF (Leukocyte and Platelet-rich fibrin). An evolution of L-PRF is the injectable PRF (i-PRF). In vivo, during the platelet clot formation, platelets are bound to β-integrin fibrin and the clot retracts itself. The PRF clot forms a solid fibrin matrix, displaying a complex tridimensional architecture. Measuring the levels of PDGF-BB, TGF-1β and IGF-1, in the PRF matrix, it was revealed that slow fibrin polymerization during PRF elaboration leads to the intrinsic......

Key Words: blood derivatives, growth factors, leucocyte and platelets-rich fibrin, injectable platelets-rich fibrin, L-PRF wound box, stem cells.

[1]. Pretorius E et al. Ultrastructural comparison of the morphology of three different platelet and fibrin fiber preparations.The Anatomical Record 2007, 290:188-198.
[2]. Del Corso M, Choukroun J, Simonpieri A, Zampetti P, Bucci Sabbatici V, Accelerazione dei processi di cicatrizzazione tissutale con un nuovo biomateriale: la fibrina ricca di piastrine (PRF). Odontoiatria 2007, 4:361-366.
[3]. Nurden AT, Nurden P, Sanchez M, Andua I, Anitua E, Platelets and wound healing. Frontiers in Bioscience 2008, 13: 3525-3548.
[4]. Crisci A, Le membrane L-PRF utili in chirurgia. Journal of Plastic Dermatology 2015, 2:75-90.
[5]. Crisci A, Placido F, Crisci M, Bosco A, A new instrument aid of plastic surgeon: membranes L-PRF (Pletelet-Rich-Fibrin). Update in Plastic Surgery 2015, 3: 162-172...

Abstract: The major objective of HRM is to achieve the success of organization through creation of motivated and competent workforce. Human Resource Management stands on the foundation of several different practices such as recruitment and selection, analyzing and designing of jobs, training and development of employees, performance appraisal, career guidance as well as planning, compensation system and participation of employees in various activities.

[1]. Miller, J. G. & Wheeler, K G. (1992). "Unraveling the mysteries of gender differences in intentions to leave the organization‟, Journal of Organizational Behaviour, Vol.13, No.5, pp.465 478.
[2]. Saxena Karunesh & Tiwari Pankaj (2009). "A Study of HRM Practices in Selected IT Companies of India", AIMS Journal of Management, Vol. 1, No. 3, pp. 29-44.
[3]. Selvaraj, M. "Total quality management in indian Commercial banks: A comparative study." journal of marketing and communication, 2009: 59-70.
[4]. Gardner, T. M., Wright, P.M., Moynihan, L.M. (2011). The impact of motivation, empowerment, and skill‐enhancing practices on aggregate voluntary turnover: The mediating effect of collective affective commitment. Personnel psychology, 64(2), 315-350.
[5]. Chinnadurai, P. (2014). HR practices in private sector banks - An empircal evidence. International Journal of Marketing, 3(4), 30– 37..

Abstract: Background- The objectives of the present study were to determine and compare the changes in serum uric acid and potassium level among patients treated with telmisartan and telmisartan with hydrochlorothiazide and to measure and compare the change in blood pressure among the two groups. Methodology- Prospective cohort of patients attending outpatient and inpatient departments in General Medicine Department of People's Hospital for a period of 18 months from November 2016 to April 2018 in the age range of 20-70 years with essential hypertension were recruited. A total of 184 patients were examined and followed up using a questionnaire. The data collected was entered and analysed in SPSS version 22.0. Results- Among 184 patients, 92 were on Group 1 (Telmisartan 40 mg (T)), 75 were on Group 2 - Telmisartan/Hydrochlorthiazide40/12.5.......

Key Words: Essential hypertension, Telmisartan, Hydrochlorthiazide, uric acid, serum electrolyte.

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