iosr-JDMS   Volume-18 ~ Issue-4 ~ April-2019

Abstract: OBJECTIVES: This study was conducted with aim of to determine the ability of BISAP (Bedside index for severity in acute pancreatitis score) score to predict mortality and severity in acute pancreatitis. MATERIAL AND METHODS: In this prospective observational study, 100 patients of acute pancreatitis were studied from July 201 to Nov 2018. . BISAP score is calculated based on data obtained within 24 hours of hospitalisation. Marshall scoring system was used to characterize organ failure. The optimal cut off score for mortality from the receiver operating characteristics (ROC) curve was used to evaluate the development of persistent organ failure and pancreatic necrosis. RESULTS: Among 100 patients, 19% patients had organ failure, 12% patients had pancreatic necrosis, 21%patients had severe acute pancreatitis........

KEY WORDS: severe acute pancreatitis, organ failure, pancreatic necrosis, mortality

[1]. Satyajit Bhattacharya.The pancrease.In; Norman S Williams,Christopher J.K.Bulstrode and P.Roman O,Connell(Editors).Bailey and Love,s Short practice of Surgery.26th edition.New York.CRC Press Taylor and Francis Group;2013.Pp.1127
[2]. Marshall JC, Cook DJ, Christou NV et al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 1995; 23: 1638–52.
[3]. Garg PK, Madan K, Pande GK, Khanna S, Sathyanarayan G, Bohidar NP, et al. Association of extent and infection of pancreatic necrosis with organ failure and death in acute necrotizing pancreatitis. Clin Gastroenterol Hepatol 2005 Feb;. 3(2): 159-166.
[4]. Yeung YP, Lam BY, Yip AW. APACHE system is better than Ranson system in the prediction of severity of acute pancreatitis. Hepatobiliary Pancreat Dis Int. 2006;5(2):294–299.
[5]. Larvin M, McMahon MJ. APACHE-II score for assessment and monitoring of acute pancreatitis. Lancet. 1989;2(8656):201–205..

Abstract: Introduction:Renal transplants have been performed over 40 years, and there is now long-term data about the bone disease in these patients. Although many aspects of Renal osteodystrophy improve, the bone density and strength may worsen due the adverse effects of immunosuppression. Material & Methods: A total of 45 patients who underwent first renal transplantation at our institute over 2 year period (January 2005 to December 2006) were recruited in the study.All the above patients were followed from 3 months before till 6 months after renal transplantation. All patients were subjected to lumbo sacral dual energy x ray absorptiometry (DEXA SCAN) one..........

Key Words: renal transplant, clinical, biochemical, skeletal abnormalities

[1]. Fan SL et al . Bone disease after kidney transplantation Bone disease of organ Transplantation . Elsevier ; 2005 : 221-242.
[2]. Cruz EAS, Lugon JR, Jorgetti V, Draibe SA, Carvalho AB. Histological evolution of bone disease 6 months after successful kidney transplantation . Am J kidney dis 2004;44: 747-756.
[3]. Parfitt, A. M. (1982). Hypercalcemic hyperparathyroidism following renal transplantation: differential diagnosis, management and implications for cell population control in the parathyroid gland. Mineral and Electrolyte Metabolism 8 , 92–112.
[4]. Julian BA, Laskow DA, Dubovsky J, Dubovsky EV, Curtis JJ, Quarles LD.Rapid loss of vertebral mineral density after renal transplantation . N Engl J med 1991; 325:544 -550.
[5]. Elisa A.S. Cruz, Jocemir R. Lugon,VandaJorgetti, Sergio A. Draibe, and Aluizio B. Carvalho. Histological Evolution of Bone Disease 6 Months After Successful Kidney Transplantation. American Journal of Kidney Diseases, Vol 44, No 4 (October), 2004: pp 747-756

Abstract: Introduction: Early appendicectomy has been found to be a safe and better alternative for management of appendicular mass in various studies in adults, while very few studies report such advantages in the paediatric population. We conducted this study to assess the safety, efficacy and need of early laparoscopic appendicectomy (ELA) in child patients with appendicular mass.
Materials And Methods: All patients with appendicular mass who underwent ELA at our institute between September 2015 and August 2018 were retrospectively reviewed. Appendicular mass was defined as a right iliac fossa mass in a case of acute appendicitis, diagnosed..........

Key Words: Appendicular mass, children, laparoscopy

[1]. Kaya B, Sana B, Eriş C, Kutaniş R. Immediate appendectomy for appendiceal mass. Ulus Travma Acil Cerrahi Derg. 2012;18:71–4. [PubMed]
[2]. Blakely ML, Williams R, Dassinger MS, Eubanks JW, 3rd, Fischer P, Huang EY, et al. Early vs interval appendectomy for children with perforated appendicitis. Arch Surg. 2011;146:660–5. [PubMed]
[3]. Garg P, Dass BK, Bansal AR, Chitkara N. Comparative evaluation of conservative management versus early surgical intervention in appendiceal mass — a clinical study. J Indian Med Assoc. 1997;95:179–80. 196. [PubMed]
[4]. Shindholimath VV, Thinakaran K, Rao TN, Veerappa YV. Laparoscopic management of appendicular mass. J Minim Access Surg. 2011;7:136–40. [PMC free article] [PubMed]
[5]. Goh BK, Chui CH, Yap TL, Low Y, Lama TK, Alkouder G, et al. Is early laparoscopic appendectomy feasible in children with acute appendicitis presenting with an appendiceal mass? A prospective study. J Pediatr Surg. 2005;40:1134–7. [PubMed]

Abstract: Background: Highly active anti-retroviral therapy (HAART) is introduced to HIV pregnant women to reduce their viral load and increase their CD4 count; this reduces the risk of mother to child transmission of HIV. Viral load is use to monitor the success of HAART. Aim: To study the incidence of Virological Success, and its independent predictors following a short course of HAART among HAART naïve HIV positive pregnant women. Study Design and Setting: This is prospective longitudinal study carried out at Nnamdi Azikiwe University Teaching Hospital, Nnewi, South East, Nigeria between January 1st, 2017 and December 31st, 2017. Methodology.......

[1]. WHO/ RHT/98.24HIV in pregnancy: a review UNAIDS/98.442
[2]. Mayaux MJ, Dussaix E, Isoet J et al . Maternal viral load during pregnancy and mother to child transmission of human immunodeficiency virus type1:the French perinatal Cohort studies. J. infect Dis, 1997;175:172-175
[3]. Marc Boucher, Mode of delivery for pregnant women infected by HIV. Journal of society of Obst. and Gynae of Canada 2001, 23(4):348-350.

[4]. ACOG Committee opinion schedule C/s and the prevention of Vertical transmission of HIV Infection. Int J Gynae-Obstet. 2001 june; 73(3):279-81.
[5]. J Ikechebelu HIV in Pregnancy. In NAUTH handbook of OBGYN care.2009; 54-58.

Abstract: Idiopathic Intracranial Hypertension is a disease of unknown etiology common in obese females and presents with headache, papilledema, raised CSF opening pressure and no abnormality on CT scan or MRI of the Brain. Sino venous abnormalities are commonly detected in patients of IIH by different neuroimaging techniques. But the exact role of these Sino venous abnormalities in the causation of the disease or whether they are an effect of the disease is not yet known. The aim of the study was to assess abnormalities in MRI with MRV in Idiopathic Intracranial Hypertension........

Key words:Idiopathic Intracranial Hypertension (IIH), MRI, MRV, BMI

[1]. Acheson JF, Green WT, Sanders MD. (1994) Optic nerve sheath decompression for the treatment of visual failure in chronic raised intracranial pressure. J Neurol Neurosurg Psychiatry 57:1426–1429
[2]. Binder DK, Horton JC, Lawton MT, McDermott MW. (2004) Neurosurgery 54:538–551
[3]. De Wecker L. (1872) On incision of the optic nerve in cases of neuroretinitis. Int Ophthalmol Cong Reps 4:11–14
[4]. Digre KB. Idiopathic Intracranial Hypertension (editorial). BMJ 2010;341:c2836
[5]. Herzau V and Baykal HE. (1998) Long-term results of optic nerve sheath fenestration in pseudotumor cerebri. Klin Monatsbl Augenheilkd 213:154–160

Abstract: Introduction : Labour pain is considered as one amongst the severe pains and managed usually by pharmacological method. The role of nonpharmacologic method-intradermal sterile water administration in the sacral region has the benefit of being nonintrusive, low-cost, simple, effective, and without serious adverse effects .Aim: To assess the efficacy of intradermal sterile water versus intramuscular pentazocine administration in sacral region (Michaelis rhomboid ) as labour analgesia.Material and method Parturients in cephalic presentation at first stage of labour were distributed alternately into two groups of fifty parturient each. Sterile water injection group of patients received 6 intradermal injections of 0.5 ml sterile water in the sacral region.In the other group pain.........

Key words: non pharmacological labour labour analgesia, intradermal sterile water administration

[1]. R. Melzack, R. Kinch, P. Dobkin, M. Lebrun, and P. Taenzer ;Severity of labour pain: influence of physical as well as psychologic variables. Can Med Assoc J. 1984 Mar 1; 130(5): 579–584.

[2]. Waldenstrom U, Borg I. M, Olsson B, Skold M, Wall S. The childbirth experience: A study of 295 mothers. Birth. 1996; 23:144–153.

[3]. Stitzel, Robert E. (2004). Modern pharmacology with clinical applications (6 ed.). Philadelphia: Lippincott Williams & Wilkins. p. 325. ISBN 9780781737623
[4]. Simkin P. Reducing pain and enhancing progress in labor: A guide to nonpharmacologic methods for maternity caregivers. Birth. 1995;22(3):161–170) .
[5]. Saxena K N, Batra S ; Intracutaneous Injections of Sterile Water over the Secrum for Labour Analgesia.Indian journal of anaesthesia 53(2): 2009, 169-73 ·.

Abstract: OBJECTIVES: Observational study of serum vitamin D levels in children under five years suffering from recurrent respiratory tract infection.METHOD: A retrospective observational study was carried out in pediatrics OPD and Inpatient department, RIMS, Ranchi.The study included 75 children with recurrent respiratory tract infection and 75 children with RTI who were selected randomly.Serum 25(OH)D levels were detected and estimated by chemiluminescence method.RESULTS: A total of 150 children of under five age group were enrolled in the study. Among 75 cases, the mean vitamin D level in patients with recurrent RTI was 12.71 ng/ml which was lower than the patients with RTI who had a mean of 14.40 ng/ml. CONCLUSION:Vitamin D is involved in regulating innate and adaptive immune functions .Children with recurrent respiratory tract infections have lower serum vitamin D levels than those with respiratory tract infection.

Keywords:Acute respiratory infection(ARI),respiratorytract infection (RTI), recurrent RTI, under five children, vitamin D

[1]. Park's textbook of Preventive and Social Medicine , 24th Edition,2017,Ch 5:177
[2]. Holick MF, Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease, The American Journal of Clinical Nutrition,80(6)2004,1678S–88.
[3]. Holick MF, Vitamin D: a millennium perspective, Journal of Cellular Biochemistry,88,2003,296–307.
[4]. Susanna Esposito and Mara Lelii, Vitamin D and respiratory tract infections in childhood,BMC Infectious Disease, 15,2015,487..

Abstract: objective was to study the correlation between Protein– creatinine ratio of spot urine sample. Correlation of the values in hypertensive pregnant females Implications and correlation with clinical scenario. Patient would be selected according to criteria for gestational hypertension. blood pressure determined by mercury sphygmomanometer on two occasions at least 4 hrs apart. The sample collected would be the first morning urine sample/ midstream sample. The cut off value of P/C would be fixed determined by receiver operating characteristics (ROC) curve. Observation shows mean value of serum creatinine in normal and pregnant females whose values are 055±.0.14 mg /dl and 0.77±0.29 mg/dl.t value is 3.75 while p value is 0.03 and hence the value is significant in this case also. The level of serum creatinine in complicated pregnancy is more as compared to normal pregnancy. value...........

Keywords: spot urine protein-creatinine ratio, proteinuria, gestational hypertension,preeclampsia, eclampsia

[1]. Review of medical physiology: W.F.Ganong 21st edition
[2]. Text Book of Medical Physiology Guyton And Hall 12th edition
[3]. Harrisson's Principle of Internal Medicine 18th edition
[4]. William's Obstetrics 22nd edition

Abstract: Background: Quality of life is a subjective multidimensional issue. It is also considered as an important prognostic factor among lung cancer patients. Measuring and understanding of the factors that might have significant impact in deciding the quality of life of lung cancer patients are therefore of utmost importance as lung cancer is one of the topmost cancers worldwide at present, considering its incidence, prevalence and mortality. Methods: An institution based cross-sectional study had been conducted in a tertiary care centre, Kolkata among 210 lung cancer:.........

Keywords: Kolkata, Lung cancer, Quality of life, Socio-economic status

[1]. Worldwide cancer data: Global cancer statistics for the most common cancers [https://www.wcrf.org/dietandcancer/cancer-trends/worldwide-cancer-data]
[2]. Polanski J, Polanska BJ, Rosinczuk J, Chabowski M, Chabowska AS. Quality of life of patients with lung cancer. OncoTargets and Therapy. 2016;9:1023–1028.

[3]. Montazeri A, Milroy R, Hole D, McEwen J, Gillis CR. Quality of life in lung cancer patients: as an important prognostic factor. Lung Cancer. 2001;31(2-3):233-240.
[4]. Hein HO, Suadicani P, Gyntelberg F. Lung cancer risk and social class. The Copenhagen Male Study--17-year follow up. Dan Med Bull. 1992;39(2):173-176.

[5]. Sharpe KH, McMahon AD, Raab GM, Brewster DH, Conway DI. Association between Socioeconomic Factors and Cancer Risk: A Population Cohort Study in Scotland (1991-2006). PLoS ONE. 2014; 9(2): e89513.

Abstract: Local anaesthesia is safely used in routine dental practice. Diplopia following LA injection is a rare but distressing complication. This article elaborates a case of diplopia following local anaesthetic injection and stresses the importance of awareness among the dental surgeons about such rare complication and its management.

Keywords: Diplopia,

[1]. Malamed S. Handbook of local anesthesia. 5th ed. St Louis. Mosby, 2004.
[2]. Steenen SA, Dubois L, Saeed P, de Lange J. Ophthalmologic complications after intraoral local anesthesia: case report and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 113: e1-5.
[3]. Boynes SG, Echeverria Z, Abdulwahab M. Ocular complications associated with local anesthesia administration in dentistry. Dent Clin North Am 2010; 54: 677-86.
[4]. Choi EH, Seo JY, Jung BY, Park W. Diplopia after inferior alveolar nerve block anesthesia: report of 2 cases and literature review. Oral Surg Oral Med Oral Pathol Oral RadiolEndod 2009; 107: e21-4.
[5]. J Dent Anesth Pain Med 2015;15(2):93-96Diplopia after inferior alveolar nerve block: case report and related physiology - Tae Min YouDepartment of Advanced General Dentistry, Dankook University, Cheonan, Korea.

Abstract: The national incidence of PIH is 15.2% in India1, while it is four times higher in primipara women than in multipara. Ocular involvement in PIH is common and the occurrence rate varies from 30-100% in different studies2.Objective of the study is to determine the prevalence of retinal changes in pregnancy induced hypertension and to study the association between retinal changes and severity of the PIH. A hospital based cross-sectional study was conducted in the setting of department of Opthamology and Obstetrics and Gynaecology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, during the year 2017.The results were analyzed using SPSS program.Majority of patients in our study were found in age group of 21 to 25 years.74% of patients were primigravida in our.......

[1]. Kamath RK, Nayak SR. Preeclampsia/Eclampsia and retinal micro vascular characteristics affecting maternal and foetal outcome: a prospective study amongst south indian pregnant women. IJIRD. 2013;2(11): 444-8.
[2]. Dornan KJ, Mallek DR, Wittmann BK. The sequelae of serous retinal detachment in preeclampsia.ObstetGynaecol. 1982;60(5):657-63.
[3]. Rasdi AR, Nik-Ahmad-Zuki NL, Bakiah S, Shatriah I. Hypertensive retinopathy and visual outcome in hypertensive disorders in pregnancy. Med J Malaysia. 2011;66(1):42-7.
[4]. Jaffe G, Schatz H. ocular manifestations of preeclampsia. Am J Ophthalmol. 1987;103(3 Pt1):309- 15. 23. Reddy SC. Raghavamma TV. Retinal detachment in preeclampsia- a case report.JObstetGynaec of India. 1981;31(3):501-3.
[5]. McEvoy M, Runicman J, Edmonds DK, Kerin JF. Bilateral retinal detachment in association with preeclampsia.AustNZ J ObstetGynaecol. 1981;21(4):246-7..

Abstract: Composite restorations are widely used in conservative dentistry because it is esthetically pleasing, bonds to the tooth, mercury free, requires only minimal invasive procedure, ease of repair, lack of corrosion and cost effective. Dr.RichardPrice 2(013) has described four variables that affect light curing. They are Curing light , Operator technique , Restoration location and Energy required by the resin.These have been characterised as the four "CORE‟ variables that affect adequate light-curing . Aims of light curing a Resin based Composite is achieving uniform and high monomer conversion to full depth of the RBC, the shortest possible exposure time and low shrinkage stress. Degree of conversion (dc) is the Conversion of monomer chains into polymers

[1]. Degree of conversion and residual stress of preheated and room-temperature composites. Indian J Dent Res 2007;18:173-6. Prasanna N, Pallavi Reddy Y, Kavitha S, Lakshmi Narayanan L.
[2]. Dentin bond strength and degree of conversion evaluation of experimental self-etch adhesive systems. J ClinExp Dent. 2015;7(2):e243-9. Yazdi FM, Moosavi H, Atai M, Zeynali M.
[3]. Evaluation of degree of conversion and hardness of dental composites photo-activated with different light guide tips .European journal of dentistry
[4]. MaríliaRegaladoGalvão, Sergei GodeiroFernandesRabeloCaldas,Vanderlei Salvador Bagnato,Alessandra Nara de Souza Rastelli,and Marcelo Ferrarezi de Andrade .J EsthetRestor Dent. 2002;14(5):286-95.
[5]. Polymerization efficiency of LED curing lights..

Abstract: The omphalomesenteric duct(OMD) more commonly referred as vitelline duct/ vitellointestinal duct is a remnant of the embryonic yolk sac and is considered a very unusual congenital anomaly occurring in less than 2% of population where it persists as embryonic yolk stalk. Patent vitellointestinal duct causing intestinal obstruction is a very rare condition in an adolescent patient. We have reported an extremely uncommon case of persistent vitellointestinal duct uncommonly causing small intestinal obstruction in an adolescent age group where exploratory laparotomy was performed which showed dilated jejunum and proximal ileum with collapsed distal ileum because of a presence.........

[1]. F. Sawada, R. Yoshimura, K. Ito, K. Nakamura, H. Nawata, K. Mizumoto, et al., Adult case of an omphalomesenteric cyst resected by laparoscopic-assisted surgery, World J. Gastroenterol. 12 (5) (2006) 825.
[2]. T.C. Moore, Omphalomesenteric duct malformations, Seminars in Pediatric Surgery [Internet] (1996) 116–123 [cited 2017 May 22].
[3]. D.W. Vane, K.W. West, J.L. Grosfeld, Vitelline duct anomalies: experience with 217 childhood cases, Arch. Surg. 122 (5) (1987) 542–547.
[4]. O. Jalil, R. Radwan, A. Rasheed, M.R. Nutt, Congenital band of the vitelline artery remnant as a cause of chronic lower abdominal pain in an adult: case report, Int. J. Surg. Case Rep. 3 (6) (2012) 207–208.
[5]. H. Markogiannakis, D. Theodorou, K.G. Toutouzas, P. Drimousis, S.G. Panoussopoulos, S. Katsaragakis, Persistent omphalomesenteric duct causing small bowel obstruction in an adult, World J. Gastroenterol. 13 (15) (2007) 2258..

Abstract: The tender Catha edulis leaves(Khat) have stimulatory properties due to the presence of alkaloid called cathinone, which is known to have a stimulating effect at lower dosages and can act as depressant if consumed at higher quantities. This study was aimed at assessing the effect of khat leaf extract on learning and memory of the rats. The study was conducted in 40 adult male Wistar rats. The rats were randomly assigned to eight groups, four groups each for RA Maze and T MAZE trails respectively. The calculated dosages were 100mg/kg Bwt (T1), 200 mg/kg Bwt (T2), 300mg/kg Bwt (T3) and control group were provided with normal saline. At the end of the experiment the rats were sacrificed and the hippocampus CA3 region of brain was identified and thereafter processed for.......

Keywords: Wistar rats, Khat extract, learning, memory, Hippocampus

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Abstract: Le traitement orthodontique fixe peut provoquer une détérioration temporaire de l'hygiène buccale avec des changements inflammatoires gingivaux et des déminéralisations tissulaires. Cette étude clinique prospectif contrôlé non randomisée ; a déterminé le taux de décalcification pendant le traitement orthodontique (durée moyenne, 18 mois) chez 75 patients, les adolescents sélectionnés répartis en 3 groupes de 25 patients chacun ; deux groupes témoins : dans le groupe 1 tous les patients sont indemnes de caries, et le groupe 2 les patients présentent des lésions carieuses, et un groupe expérimental dans lequel tous les patients vont suivre des mesures d'hygiène rigoureuses et un apport de fluor supplémentaire. La régression logistique multivariée ajustée............

[1]. Opsahl Vital S, Haignere-Rubinstein C, Lasfargues J J, Chaussain C. Caries risk and orthodontic treatment, International Orthodontics, Volume 8, Issue 1, March 2010, Pages 28-45.
[2]. Bourzgui F, Sebbar M, Hamza M. Le risque carieux en orthodontie : étude descriptive d'un échantillon de 155 patients.Revue de Stomatologie et de Chirurgie Maxillo-faciale, Volume 111, Issues 5–6, November–December 2010, Pages 276-279
[3]. Bahoum A., Bahije L, Zaoui F. Les déminéralisations amélaires en orthodontie. Rev Mens Suisse Odonto-stomatol Vol. 122 10/2012.
[4]. Flamant R, Schwartz D, Lellouch J. L'essai thérapeutique chez l'homme.1970.
[5]. Kukleva M, Shetkova D G, Beev V H. Comparative age study of the risk of demineralization during orthodontic treatment with brackets. Folia Med (Plovdiv). 2002; 44(1-2):56-9..

Abstract: Background: Temporomandibular joint disorders (TMDs) causes a problem in chewing system which is comprised of the temporomandibular joint and soft tissue around it. Aim: The present study aimed to explore the relationship of Depression and Quality of Life in patients with Temporomandibular Joint Disorders. Methodology: This is the cross-sectional study which included all consecutive patient with TMD, reported in the department of oral and maxillofacial surgery with a duration of 3 months and 30 age-sex match healthy controls. Both the groups were assessed with the Hamilton Depression Rating Scale (HDRS) and Quality of Life Index (WHOQOL-100).........

Key words: Temporomandibular joint disorders, Depression, Quality of life

[1]. Okeson JP. Management of temporomandibular disorders and occlusion. St Louis, MO: Mosby; 2008. pp. 129–64. p.
[2]. Rollman GB, Gillespie JM: The Role of Psychosocial Factors in Temporomandibular Disorders. Current Review of Pain 2000, 4:71–81
[3]. Dworkin SF: Temporomandibular disorders: a problem in dental health. In Psychosocial Factors in Pain: Critical Perspectives. Edited by Gatchel RJ, Turk DC. New York: Guilford Press; 1999:213–226.

[4]. LeResche L. Epidemiology of temporomandibular disorders: implications for investigation of etiologic factors. Crit Rev Oral Biol Med. 1997;8:291–305.

[5]. Dworkin SF, Huggins KH, LeResche L, Von Korff M, Howard J, Truelove E, et al. Epidemiology of signs and symptoms in temporomandibular disorders: clinical signs in cases and controls. J Am Dent Assoc. 1990;120:273–81..

Abstract: Coronary heart disease is a major health problem in the world. Thrombolysis by fibrinolytic agents is still the treatment for acute myocardial infarction in India. Several factors influence the success of re perfusion in a case of ST elevation myocardial infarction. Among these Killip class has great influence on thrombolysis outcome. So, in the this study, the influence of Killip class on the success of thrombolysis by Inj.Streptokinase in ST elevation myocardial infarction. Patients have been studied and correlated with the data obtained from subjects from similar studies.

Key words: Coronary heart disease, Killip class

[1]. Gibson CM: Has my patient achieved adequate myocardial reperfusion?. Circulation 2003; 108:504-507.
[2]. Gibson CM, Murphy SA, Rizzo MJ, Ryan KA, Marble SJ, McCabe CH, Cannon CP, Van de Werf F, Braunwald E: Relationship between TIMI frame count and clinical outcomes after thrombolytic administration. Thrombolysis In Myocardial Infarction (TIMI) Study Group. Circulation 1999; 99:1945-1950.
[3]. Gibson CM, Murphy S, Menown IB, Sequeira RF, Greene R, Van de Werf F, Schweiger MJ, Ghali M, Frey MJ, Ryan KA, Marble SJ, Giugliano RP, Antman EM, Cannon CP, Braunwald E: Determinants of coronary blood flow after thrombolytic administration. TIMI Study Group. Thrombolysis in Myocardial Infarction. J Am CollCardiol 1999; 34:1403-1412.
[4]. Gibson CM, Murphy SA, Kirtane AJ, Giugliano RP, Cannon CP, Antman EM, Braunwald E: Association of duration of symptoms at presentation with angiographic and clinical outcomes after fibrinolytic therapy in patients with ST-segment elevation myocardial infarction. J Am CollCardiol 2004; 44:980-987.
[5]. Angeja BG, de Lemos J, Murphy SA, Marble SJ, Antman EM, Cannon CP, Braunwald E, Gibson CM: Impact of diabetes mellitus on epicardial and microvascular flow after fibrinolytic therapy. Am Heart J 2002; 144:649-656...

Abstract: Coronary heart disease is a health epidemic present worldwide. Thrombolysis by fibrinolytic agents is still the preferred mode of treatment in India. Several factors contribute to the success of re perfusion in a case of ST elevation myocardial infarction including age , sex , time taken from onset of pain to treatment , co morbidities like diabetes and systemic hypertension , lifestyle changes like smoking , whether Anterior wall myocardial infarction or Inferior wall myocardial infarction ,etc . So , in the following study , the influence of Systemic hypertension on the success of thrombolysis by Inj.Streptokinase in ST elevation myocardial infarction patients have been analysed and correlated with the data obtained from subjects from similar studies

Key words: Coronary heart disease , Steptokinase

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