iosr-JDMS   Volume-18 ~ Issue-4 ~ April-2019

Abstract: DLE/CCLE is a benign disorder of skin most frequently involving the face, characterized by well defined red scaly plaques of variable sizes that heal with atrophy, scarring and pigmentary changes. The histology is characteristic. Squamous cell carcinoma can rarely arise within a longstanding DLE plaque in the skin particularly over scalp, ears , lips and nose . It presents as an enlarging warty growth or ulcer. We report a case of squamous cell carcinoma which developed on lesion of discoid lupus erythematosus within a short period of time.

KEY WORDS: Discoid lupus erythematosus, Squamous cell carcinoma, Carpet tack sign

[1]. Winfield H, Jaworsky C. Connective tissue diseases. In :Elder DE, Elenitsas R, Johnson BL, Murphy GF, Xu X (eds). Lever's histopathology of the skin, 10th ed. Philadelphia: Lippincott Williams and Wilkins; 2009: 279-310
[2]. Cassarino DS, Derienzo DP, Barr RJ. Cutaneous squamous cell carcinoma: A Comprehensive clinicopathologic classification. J CutanPathol. 2006;33:191-206.
[3]. Grover S, Murthy PS, Rajagopal R, Jalpota YP, Sudha KV. Discoid lupus erythematous leading to squamous cell carcinoma.Med J Armed Forces India. 2007;63:184-5.
[4]. Dhingra M, Bhalla M, Thami GP, Mittal P. Metastasizing squamous cell carcinoma arising from chronic discoid lupus erythematosus plaque of recent onset. Indian J DermatolVenereolLeprol. 2011;77:626.
[5]. Bhat MR, Hulmani M, Dandakeri S, Kambil SM, Gatti R. Disseminated discoid lupus erythematousleading to squamous cell carcinoma. Indian J Dermatol. 2012:57:158-61..

Abstract: Background: Urinary tract infection is one of the most common infections in children. Early diagnosis and appropriate treatment can significantly decrease late serious complications. Aim & Objective: The primary aim of this study was to see the causative organisms and their culture & sensitivity pattern, so that pediatrician can choose the most appropriate and safe antibiotic when treating a children with UTI in this area. Material and Methods: All children from 1 month to 15 years of age with culture positive urinary tract infections who were admitted to Pediatric ward from 13th April 2018 to 12th February 2019 were included. The causative organisms for urinary tract infection along with its antibiotic sensitivity pattern were retrospectively reviewed and analyzed..........

Key Words: Antibiotics sensitivity, Organism, Resistance, UTI.

[1]. Supriya S. Tankhiwale, Suresh V. Jalgaonkar, Sarfraz Ahamad and Umesh Hassani. Evaluation of extended spectrum beta lactamase in urinary isolates. Indian J Med Res 2004; 120: 553-556.
[2]. Kahlmeter G. Eco. Sens. An international survey of the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections: the ECO.SENS Project. J Antimicrobial Chemother 2003; 51: 69-76.
[3]. Chakupurakal R, Ahmed M, Sobithadevi DN, Chinnappan S, Reynolds T. Urinary tract pathogens and resistance pattern. J Clin Pathol 2010; 63: 652-654.
[4]. Lutter SA, Currie ML, Mitz LB, Greenbaum LA. Antibiotic resistance patterns in children hospitalized for urinary tract infections. Arch Pediatr Adolesc Med 2005; 159: 924-928.
[5]. Arvind Bagga. Consensus Statement on Management of Urinary Tract Infections: Indian Pediatrics 2001; 38: 1106-1115.

Abstract: Background: Arthroscopic anterior cruciate reconstruction has become one of the most successful surgical techniques in sports medicine however initial secure graft fixation is essential for the success of any ACL reconstruction. Objective: The study was done to evaluate the functional outcome of arthroscopic ACL reconstruction using hamstring graft fixed with endobutton for femur and interference screw and suture post for tibial fixation. Material and methods: From 2013to 2016, 30 patients underwent ACL reconstruction using hamstring graft fixed with endobutton for femur and interference screw for tibial fixation and the outcome was observed using IKDC knee score 2000..........

Key Words: Anterior cruciate ligament, hamstring graft, endobutton, arthroscopy

[1]. Meighan AA, Keating JF, Will E.Outcome after reconstruction of the anterior cruciate ligament in athletic patients. A comparison of early versus delayed surgery. Bone Joint Surg Br 2003;85:521-4.
[2]. Satku K, Kumar VP, Ngoi SS. ACL injuries. To counsel or to operate? J Bone Joint Surg Br 1986;68:458- 61.
[3]. Howe, Johnson, Kaplan. ACL reconstruction using Quadriceps patellar tendon graft. Part I. Long term follow up. Am J of Sports Med 1991;19:447-57.
[4]. Michael Wagner, Max J. Hamstring tendon versus patellar tendon anterior cruciate ligament reconstruction using biodegradable interference fit fixation. Am J Sports Med 2005;33(9):1327-1336.
[5]. Brier SJ, Warren RF, Pavlov H, Panareillo R. Reconstruction of the chronically insufficient anterior cruciate ligament with the central third of the patellar ligament. J Bone Joint Surg Am 1991;73:278- 86..

Abstract: The skin being the largest organ of the body, often provides a clue to the underlying systemic diseases, and hence cutaneous manifestations of systemic diseases are frequently encountered by dermatologists. The liver is the second largest organ of the body, and liver dysfunction often results in changes in the body's largest organ, the skin. The present study was aimed to study the cutaneous manifestations of chronic Liver Disease. Materials and method: this study was conducted in the tertiary care centre of Jharkhand. 100 patients were included in the study after fullfilling the exclusion and inclusion criteria. Results: 100 patients who was diagnosed.....

Key words: Chronic liver disease(CLD), Cutaneous manifestations, Hepatitis

[1]. Robin AC, Graham B, Sarkany I. The Hepatobiliary system and the skin. In: Freedberg IM, Eisen AZ, Wolff K et al. Fitzpatrick's Dermatology in General Medicine, 6 th edn. New York:( McGrawHill;1998.) p 1012-23.
[2]. Weismann K, Graham RM. Systemic disease and the skin. In: Champion RH, Burton JL, Burns DA, Breathnach SM. Textbook of Dermatology, 6th edn. (London: Blackwell Science; 1998). p 2311-73.
[3]. Agnello V, Chung RT, Kaplan LM. A role for hepatitis C virus infection in type II cryoglobulinemia. N Engl J Med 1992; 327: 1490-5.
[4]. Colinogilvie D, Cristopher C, Evans CC, eds. Chamberlain's Symptoms & Signs in Clinical Medicine, 12th edn. (Buttterworth: Heinsmann; 1997.)
[5]. Lawarance S, FriedmanL S, eds. Current Medical Diagnosis and Treatment, 41st edn. (New York: McGraw-Hill; 2002)...

Abstract: Acute myocardial infarction is a major health disease in the world. Thrombolysis by fibrinolytic agents is the main treatment for myocardial infarction . Success rate of re perfusion in a case of ST elevation myocardial infarction is influenced by many factors.Among these Window period has great influence on thrombolysis outcome . In this study , the influence of Window period on the success of thrombolysis in ST elevation myocardial infarction have been studied and correlated with similar studies

Key words:Acute myocardial infarction , Window period.

[1]. Mensah GA, Hand MM, Antman EM, Ryan J, TJ, Schriever R, Smith J, SC, Jacobs AK: Recommendations for the establishment of ideal systems of care to increase the number of ST-segment elevation myocardial infarction patients with timely access to primary percutaneous coronary interventions: the patient and public perspective. Circulation, in press. 2007.
[2]. Robertson RM, Taubert KA: Warning signs for heart attack and stroke: what more can we do?. J CardiopulmRehabil 2005; 25:40-42.
[3]. Moser DK, Kimble LP, Alberts MJ, Alonzo A, Croft JB, Dracup K, Evenson KR, Go AS, Hand MM, Kothari RU, Mensah GA, Morris DL, Pancioli AM, Riegel B, Zerwic JJ: Reducing delay in seeking treatment by patients with acute coronary syndrome and stroke: a scientific statement from the American Heart Association Council on cardiovascular nursing and stroke council. Circulation 2006; 114:168- 182.
[4]. National Heart Lung and Blood Institute : Act in time to heart attack signs. Accessed on: 4/16/06. Available at: www. nhlbi.nih.gov/ actintime
[5]. Hallstrom AP, Ornato JP, Weisfeldt M, Travers A, Christenson J, McBurnie MA, Zalenski R, Becker LB, Schron EB, Proschan M: Public-access defibrillation and survival after out-of-hospital cardiac arrest. N Engl J Med 2004; 351:637-646.

Abstract: Juvenile nasopharyngeal angiofibroma(JNA) is a benign ,richly vascularised mesenchymal neoplasm. Most commonly occurs in adolescent males. It originates mostly from the posterolateral wall of the nasopharynx and extents into the surrounding tissue. Extranasopharyngeal angiofibroma(ENA) is an uncommon tumor with only 65 cases being reported in world literature, in which maxillary sinus is the common site and nasal septum is found to be an extremely rare site. Here we report a case of 15 year old male patient with extranasopharyngeal angiofibroma arising from nasal septum. This case is being published for its rarity and unusual site of origin..

Key words: extranasopharyngeal angiofibroma(ENA), nasal septum ,unusual site.

[1]. Gullane PJ, Davidson JO. "Dwyer T, Forte V. Juvenileangiofibroma: A review of literature and a case series report. Laryngoscope 1992;102:928-33.
[2]. De Vincentiis G, Pinelli V. Rhinopharyngeal angiofibroma in the pediatric age group. Clinical-statistical contribution. Int J Pediatr Otorhinolaryngol 1980;2:99-122.
[3]. Windfuhr JP, Remmert S. Extranasopharyngeal angiofibroma: Etiology, incidence and management. Acta Otolaryngol 2004;124:880-89.
[4]. Huang RY, Damrose EJ, Blackwell KE, Cohen AN, Calcaterra TC. Extranasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol 2000;561:59-64.
[5]. Somdas MA, Ketenci I, Unlu Y, Canoz O, Guney E.Extranasopharyngeal angiofibroma originating from the nasal septum. Otolayngol Head Neck Surg 2005;133:1-2.

Abstract: Background: Previous epidemiological studies suggest an association between psoriasis and metabolic syndrome and risk of subclinical atherosclerosis. However, there is a paucity of data in the Indian population on these associations. Objectives: To evaluate the prevalence of metabolic syndrome in patients with chronic plaque psoriasis compared to healthy controls and to correlate the prevalence of metabolic syndrome with severity of psoriasis as well as to assess the levels of C-reactive protein as a marker of disease severity. Methods: A hospital-based cross-sectional study was performed on 100 patients with chronic plaque type psoriasis and 100 controls. Psoriasis was categorized as mild, moderate and severe based on psoriasis area and severity index (<10, 10–14 and >14, respectively) and as disease of short (<1 year), intermediate (1–3 years) and long duration (>3 years.........

Key words: Metabolic syndrome, psoriasis, comorbidities, subclinical atherosclerosis

[1]. Davidovici BB, Sattar N, Prinz J, Puig L, Emery P, Barker JN, et al. Psoriasis and systemic inflammatory diseases: Potential mechanistic links between skin disease and co‑morbid conditions. J Invest Dermatol 2010;130:1785‑96.
[2]. Ortonne JP. Recent developments in the understanding of the pathogenesis of psoriasis. Br J Dermatol 1999;140Suppl 54:1‑7.
[3]. Gerkowicz A, Pietrzak A, Szepietowski JC, Radej S, Chodorowska G. Biochemical markers of psoriasis as a metabolic disease. Folia HistochemCytobiol. 2012;50:155–70.
[4]. Tagami H, Aiba S. Psoriasis. In: Bos JD, editor. Skin Immune System (SIS). 2nd ed., Vol. 148. Boca Raton, New York: CRC Press LLC; 1997. p. 523‑30.
[5]. Jullien D. Psoriasis physiopathology. J EurAcadDermatolVenereol 2006;20:10‑23.

Abstract: OBJECTIVES: Observational study of serum vitamin D levels in children under five years suffering from pneumonia METHOD: A retrospective observational study was carried out in pediatrics OPD and Inpatient department, RIMS ,Ranchi.The study included 95 children with pneumonia and 95 healthy controls who were selected randomly.Serum 25(OH)D levels were detected and estimated by chemiluminescence method. For categorical analysis of the vitamin D status , cut off values of ≥30 ng/mL for sufficiency, 20–30 ng/mL for insufficiency, 10–20 ng/mL for deficiency, and ≤10 ng/mL for severe deficiency were set .RESULTS: A total of 190 children.....

Keywords: pneumonia, under five children, vitamin D

[1]. Park's textbook of Preventive and Social Medicine , 24th Edition,2017,Ch 5:177
[2]. Holick MF, Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease, The American Journal of Clinical Nutrition,80(6)2004,1678S–88.
[3]. Holick MF, Vitamin D: a millennium perspective, Journal of Cellular Biochemistry,88,2003,296–307.
[4]. Susanna Esposito and Mara Lelii, Vitamin D and respiratory tract infections in childhood,BMC Infectious Disease,15,2015,487

Abstract: Background: The salivary glands are one of the few tissues in the body that are subjected to diverse and heterogeneous range of tumors and tumor like conditions. The relative infrequency of these tumors makes their diagnosis and management quite complicated. Fine needle aspiration cytology (FNAC) is a useful diagnostic procedure which has a recognized role in the evaluation of salivary gland lesions. A pre-operative diagnosis about nature of lesion, whether benign or malignant, will help in making decision about proper management of patient........

Keywords: Salivary gland tumors, FNAC,

[1]. Ahmed S, Lateef M, Ahmed R. Clinicopathological study of primary salivary gland tumors in Kashmir. J-K practitioner. 2002;9:231-3.
[2]. Frable MA, Frable WJ. Fine needle aspiration biopsy of salivary galands. Laryngoscope. 1991;101: 245-9.
[3]. Cristallini EG, Ascani S, Farabi R, Liberati F, Maccio T, Peciarolo A. Fine needle aspiration biopsy of salivary gland 1985-1995. Acta Cytol. 1997;41:1421-25.
[4]. Stewart CJR, Mackenzie K, McGarry GW, Mowat A. Fine needle aspiration cytology of salivary glands: A review of 341 cases. Diagn Cytopathol. 2000; 22:139-46.
[5]. Rajwanshi A, Gupta K, Gupta N, Shukla R, Shrinivasan R, Nijhawan R. Fine needle aspiration cytology of salivary glands: Diagnostic pitfalls- Revisited. Diagn Cytopathol. 2006;34:580-84.

Abstract: Background: The high incidence of intraoperative nausea and vomiting in cesarean section under spinal anaesthesia is distressing to the parturients and disturbing to the surgeons by causing protrusion of abdominal viscera rendering surgery more difficult and increasing the risk of visceral injuries, aspiration being an additional hazard.Many methods have been used to reduce the incidence of nausea and vomiting but they add to cost and side effects. Intrathecal lipophilic opioids added to bupivacaine as an adjuvant have been shown to reduce incidence of nausea and vomiting, it is inexpensive has few serious side effects and is established as adjuvant.Hence could be good alternative for prophylaxis of emetic episodes in cesarean section under spinal anaesthesia, thus basis of our study...........

Key Words;Nausea, vomiting,cesarean section, spinal anaesthesia,fentanyl,bupivacaine,belville secore,rescue antiemetic

[1]. Lussos S A, Bader A M, Thornhill M L, Datta S. The antiemetic efficacy and safety of prophylactic metoclopramide for elective cesarean delivery during spinal anesthesia. Reg. Anesth 1992; 17: 126–130.
[2]. Eun Jin Kim, Justin Sang Ko, Chung Su Kim, Sang Min Lee, Duck Hwan Choi. Combination of antiemetics for prevention of post-operative nausea and vomiting in high risk patients. J Korean Med Sci 2007; 22: 878-882.
[3]. Harmon D, Ryan M, Kelly A, Bowen M. Acupressure and prevention of nausea and vomiting during and after spinal anaesthesia for cesarean section. Br J Anaesth 2000; 84: 463–467.
[4]. Ky Ho, J W Chiu. Multimodal antiemetic therapy and emetic risk profiling. Annals Academy of Medicine Singapore 2005; 34:196- 205.
[5]. Balki M, Dhumne S, Kasodekar S, Kingdom J, Windrim R, Carvalho JCA. Intraoperative nausea and vomiting during cesarean section under regional anaesthesia. International journal of obstetrics anaesthesia 2005; 14: 230 -341

Abstract: Blair et al defined basicervical fracture neck of femur as proximal femoral fracture through the base of the femoral neck at its junction with the intertrochanteric region1. Whereas Parker et al defined these fractures as fractures in which the fracture line runs along the line of anterior attachment of the capsule2. Basicervical fracture neck of femur is a challenging problem as compared to intertrochanteric fractures,basicervical fractures have greater instability and poor outcomes3, 4, 5. Femoral neck fractures in young patients.........

[1]. Blair B, Koval KJ, Zuckerman JD, Basice cervical fracture of proximal femur. A biomechanical study of 3 internal proximal techniques ClinOrthopRelat Red. 1994;306:256-263.
[2]. Parvez H, Parker MJ, Pryor GS, al. Classification of trot enteric fracture of proximal femur: a study of reliability of current systems.injury.2002;33:713-715.doi:10.1016/s0020-1383(02)00089-x.
[3]. Gill JM, Johnson GR, Sher JL, Kornjaca NA. Biomechanical aspects ofintertrochantric fractures. J Biomed Eng. 1989;11:235-239. doi:10.1016/0141-5425(89)90149-0.
[4]. Su BW, Heyworth BE, Protopsaltis TS, et al. Basicervical versus intertrochanteric fracture: an analysis of radiographic and functional outcomes. Orthopedics. 2006;29:919-925.
[5]. Ly TV, Swiontkowski MF. Management of femoral neck fracture in young adult. IJO. 2008;42:3-12..

Abstract: Background: Small cell lung cancer (SCLC) is a major cause of cancer deaths and accounts for 20% to 25% of all lung cancer1. It follows a more rapid clinical course than non-small-cell lung cancer. In contrast to non-small-cell lung cancer, however, small-cell lung cancer is very sensitive to cytotoxic agents and radiation therapy2. Material And Methods: This Quasi-experimental prospective study done in the oncology department of different hospital in Dhaka to evaluate the clinical response and toxicities between Cisplatin plus Etoposide Versus Paclitaxel plus Carboplatin in the...............

[1]. Perez CA, Brady LW, Halperin EC, Schmidt-Ullrich RK, editors. Principles and Practice of Radiation Oncology. 6th ed. Philadelphia, USA: Lippincort-Raven publisher;2013.
[2]. Casciato DA, Agha ME, Albert SR, et al. Manual of Clinical Oncology. 7th ed. Philadelphia, USA: Lippincort Williams and Wilkins; 2012. P.222.
[3]. Rubin P, Bakemeier RF, Basil J, et al. Clinical Oncology: A Multidisciplinary Approach for Physicians and sutdents. 9th ed. Philadelphia, USA: W.B. Saunders Company;2001. P.8.
[4]. Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, Mckenna WG, editors. Clinical Oncology. 3rd ed. Philadelphia, USA: Elsevier Inc; 2004.p.1655.
[5]. Bomford CK, Kunkler HI, Hancock BW. Walter and Miller's Walter Textbook of Radiotherapy. 7th ed. Edinburgh, London: Churchill Livingstone. 2012. p.421-423..

Abstract: The purpose of this study was to determine the relationship between matrix metalloproteinase 9 and atrial fibrillation recurrence after catheter ablation. Background–Matrix metalloproteinase – 9 (MMP-9)is involved in extracellular matrix remodeling whichis considered to be a marker of extracellular collagen degradation. Methods– An enzyme-linked immunosorbent assay prior to a radiofrequency catheter ablation (RFA) procedure was used for measuring the serum level of MMP-9 in 210 patients: 80 patients without history of atrial fibrillation (AF) and 80 patients with idiopathic AF (paroxysmal AF – 30, persistent AF – 32, long-standing AF – 35 and permanent AF – 33). Their relationship with intraoperative efficacy and recurrence of AF was evaluated throughout the entire observation period...........

Key words: metalloproteinase-9, recurrence, fibrillation, ablation, matrix.

[1]. Chugh SS, Havmoeller R, Narayanan K, Singh D, Rienstra M, Benjamin EJ, Gillum RF, Kim YH, McAnulty JH Jr, Zheng ZJ, Forouzanfar MH, Naghavi M, Mensah GA, Ezzati M, Murray CJ. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation 2014; 129:837–847.
[2]. Laila Staerk, Jason A. Sherer, DaraeKo, Emelia J. Benjamin, Robert H. Helm Atrial Fibrillation Epidemiology, Pathophysiology, and Clinical Outcomes. Circulation 2017; 120:1501-1517.
[3]. Pappone C, Vicedomini G, Augello G, Manguso F, Saviano M, Baldi M, et al. Radiofrequency catheter ablation and antiarrhythmic drug therapy: a prospective, randomized, 4-year follow-up trial: the APAF study. CircArrhythmElectrophysiol. 2011;4(6):808-14.
[4]. Elayi CS, Verma A, Di Biase L, Ching CK, Patel D, Barrett C, et al. Ablation for longstanding permanent atrial fibrillation: results from a randomized study comparing three different strategies. Heart Rhythm. 2008;5(12):1658-64.
[5]. Calkins H, Kuck KH, Cappato R, Brugada J, Camm AJ, Chen SA, et al. 2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. Europace. 2012;14(4): 528-606...

Abstract: Isolated corrosive antral strictures occur due to pyloroplasm.It is less common than concomitant injury to the oesophagus. However thought the pathology due to corrosives is the same,the management of isolated antral corrosive stricture is different from oesophageal strictures. We wish to present our experience in the management of isolated gastric strictures from 2008-2018. 27 patients(14 M:13 F) were described to be those with isolated gastric corrosive strictures. 14 of these patients were taken for primary procedure without any enteral access in a median of 11 weeks(range-4-360 weeks). 13 patients had enteral access (13-FJ,2-FJ+ Venting gastrostomy) done at a mean of 6.3 weeks (0.5-24 weeks). The time from EA (enteric access) to definite surgery.............

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[5]. Ozcan C, Erqun O, Sen T, Mutaf O. Gastric outlet obstruction secondary to acid 10 88%. In a recent study, gastric resection was performed in 59%, ingestion in children. J PediatrSurg 2004;39:1651–3..