iosr-JDMS   Volume-19 ~ Issue-5 ~ May 2020

Abstract: SAAAB, SAABFAT6 and SAABMAL Herbal supplements have been used in the treatment of Cancers of different shades and classicifications, Asthma,Hepatitis B and C,HIV and AIDS,as well as Malaria with improved clinical features and good laboratory results.The constituent of these herbal supplements includes Lemon leaf,BitterLeaf,GarlicBulb,Sesameseeds,AloeVera,Millet,Soyabean and AmaranthusCaudatus.The aim of the research includes,to promote the use of African polyherbal formulations in the treatment of infectious diseases like Hepatitis B,HIV& AIDs and Covid -19 via inhibition of viral growth and replication ;to promote the the use of African polyherbal formulations in the treatment of Cancers; to promote the the use of African polyherbal formulations in the treatment of Malaria.The objectives includes, to recommend the use of SAAAB ,SABFAT6 and SABMAL in the treatment of Covid-19;to determine the use of SAAAB in the treatment of Hepatitis B and probably Covid-19 ;to determine the use of SAAAB in the treatment of HIV and AIDs and probably Covid-19;to determine the.....

Keywords: Covid-19, SAAAB, SAABFAT6 and SAABMAL HERBAL SUPPLEMENTS

[1]. Amodu B. et al. 2014.Evaluation of SAAAB as a polyhedral formulation for Treatment of Ataxia Markers IOSR journal of Pharmacy and Biological Sciences (9)3
[2]. Amodu et al 2014.Ethnopharmacological and Preclinical Studies on HeptoSAAB used in LeishmaniasisIOSR journal of Pharmacy and Biological Sciences (9) 3
[3]. Byeon S. Ullrich S.E. Waller T.A.Bucana C.D. &Strickland F.M. 1988.Aloe barbadensis extracts reduce the production of interleukin-10 after exposure to ultraviolet radiation. J Invest Dermtol.(1)10:811–7.
[4]. Chang C.K.HouM.H.Chang C.F. Hsiao C.D. Huang T.H. 2014. "The SARS coronavirus nucleocapsid protein--forms and functions". Antiviral Research. (10)3: 39–50. doi:10.1016/j.antiviral.2013.12.009. PMID 24418573.
[5]. .Chithra P. Sajithlal G.Chandrakasan G.1998. Influence of aloe vera on the glycosaminoglycans in the matrix of healing dermal wounds in rats. J Ethnopharmacol. (59)179–86

Abstract: Background: Volume guaranteed (VG) is a novel mode, best described as a dual loop synchronized modality that ventilates with time cycled pressure limited ventilation. It provides automatic adjustment of the peak inspiratory pressure for ensuring a minimum set tidal volume. There are limited data about the effects of VG ventilation on required duration of ventilation and short term neonatal outcomes in preterm infants with respiratory distress syndrome (RDS). Objective: The objective of this study was to evaluate the effect of VG ventilation on required duration of ventilation. Methods: This prospective randomized comparative study was conducted at level III b NICU of Deenanath Mangeshkar Hospital & Research Center.....

Key words: SIPPV-Synchronized Intermittent Positive Pressure Ventillation, VG- Volume Guarantee

[1]. Sekar KC. Trends in conventional mechanical ventilation and pulmonary graphics in the newborn. Chin Med J 2010; 123: 3319–3325.
[2]. Keszler M. State of the art in conventional mechanical ventilation. J Perinatol 2009; 29: 262–275.
[3]. Giuliani R, Mascia L, Recchia F, Caracciolo A, Fiore T, Ranieri VM. Patientventilator interaction during synchronized intermittent mandatory ventilation . Effects of flow triggering . Am J Respir Criti Care Med. 1995 Jan; 151(1):19.
[4]. Hummler H, Schulze A. New and alternative modes of mechanical ventilation in neonates . Semin Fetal Neonatal Med . 2009 Feb 28 (Vol. 14, No. 1, pp. 4248) . WB Saunders.
[5]. Choukroun ML, Llanas B, Apere H, Fayon M, Galperine RI, Guenard H et al. Pulmonary mechanics in ventilated preterm infants with respiratory distress syndrome after exogenous surfactant administration: a comparison between two surfactant preparations. Pediatr Pulmonol. 1994 Nov 1; 18(5):2738.

Abstract: The aim of this case report, is to make a Clinical presentation of a rare case of pregnancy, followed by large intra-abdominal intestinal tumor, which compromised the pregnancy and it was the reason for premature delivery. This tumor was diagnosed in 32 estational week of the pregnancy, when patient started with the symptoms of sudden and extreme vomiting and collapsing. She was hospitalized at the Department of Pathologic Pregnancies at Gynecology and Obstetrics Clinic in Skopje, after she was sent from a Clinical Hospital- Shtip, were she was first hospitalized. During the hospitalization at our Department, she undergo several Obstetrics and abdominal ultrasound examinations, hematological examinations, serological and infective examinations, tumor markers, gastroscopy and MRI which shown large abdominal intra peritoneal tumor located under the liver...

Key Words: Pregnancy, Intra-abdominal tumor, Prematurity, Ultrasound, MRI.

[1]. Sareh Parangi M.D., Deborah Levine M.D., Antonia Henry B.A : Surgical gastrintesinal disorders during pregnancy; The American Journal of Surgery, Volume 193, Issue 2, February 2007, Page 223-232
[2]. Katherine R.Birchard, Michele A.Brown, W.Brian Hyslop: MRI of Acute Abdominal and Pelvic Pain in Pregnant Patients; American Journal of Rentgenology, February 2005, Volume 184, Number 2, Page 452-458
[3]. Steven C. Katz MD, Ronald P.De Matteo MD: Gastrointestinal Stromal tumors and Leiomiosarcomas; Journal of Surgical Oncology, 19 February 2008
[4]. Elizabeth Lazarus MD, William W. Mayo-Smith MD, Martha B.Matniero MD: CT in Evaluation of Nontraumatic Abdominal Pain in Pregnant Women; RSNA Radiology, September 2007, Volume 244, Issue 3
[5]. A.P.H. Struyk & P.E.Treffers: Laparoscopic menagment of adnexal mass during pregnancy; Acta Obstetricia et Gynecologica Scandinavia, Volume 63, 1984-Issue 5.

Abstract: Severe sepsis and septic shock causes significant mortality, morbidity and high cost of care. Traditionally, normalization of vital signs, such as blood pressure, urine output, and heart rate has been used as endpoints of resuscitation. However, critical analysis of these endpoints has revealed the inadequacy of relying solely upon vital signs in resuscitation of critically ill patients1. In the presence of normal vital parameters there is persistence of tissue hypoperfusion which leads to MODS and death.2 Many critically ill patients who are normotensive and have adequate urine output, may remain in a state of compensated shock.1 The optimal management of pediatric septic shock patients includes early recognition of inadequate tissue perfusion and its timely correction in an effort to prevent anaerobic......

[1]. Scalea TM, Maltz S, Yelon J, Trooskin SZ, Duncan AO, Sclafani SJ. Resuscitation of multiple trauma and head injury: role of crystalloid fluids and inotropes. Crit Care Med. 1994;22:1610–15.
[2]. Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypoperfusion and mortality in patients with suspected infection. Intensive Care Med. 2007;33:1892-9.
[3]. Carcillo JA, Fields AI. Task force Committee Members.Clinical practice parameters for hemodynamic support of pediatric and neonatal patients in septic shock.Crit care Med. 2002;30:1365–78.
[4]. Jocobs BK, Carver J, Wilkinson JD. Comparison of gastric intromucosal pH and standard perfusional measurements in pediatric septic shock. Chest. 1995;108:220–5.
[5]. Han YY, Carcillo JA, Dragotta MA, Bills DM, Watson RS, Westerman ME, et al. Early reversal of pediatricneonatal septic shock by community physicians is associated with improved outcome. Pediatrics. 2003;112:793–9..

Abstract: Background and objectives - Ileostomy is often constructed in emergency surgical conditions like enteric or tubercular perforations when patients present late in the course of illness to preclude primary closure. But the ostomy carries with it lot of morbidity making the quality of life poor. The early closure of ostomy can minimize the associated morbidity and help the patient to enjoy better quality of life sooner. Our aim was to prospectively compare the morbidity and mortality associated with early and delayed ileostomy closure. Methods- A total of 100 patients were selected admitted from OPD and Emergency in Department of Surgery who underwent laprotomy planned procedure and required temporary ileostomy. Period of study was two years from Dec 2017 to Dec 2019. The study group was divided into two cohorts : 40 patients in early ileostomy closure group where reversal was done in 4 weeks and.......

[1]. Alves A, Panis Y, Lelong B, Dousset B,Benoist S and Vicant E: Randomizedclinical trial of early versus delayed temporary stoma closure after proctectomy,Br J Surg, 2008; 95: 693 – 698.
[2]. Hindenburg T, Rosenberg J. Closing a temporary ileostomy within four weeks. Dan Med Bul 2010;57:1-5.
[3]. Poskus E, Kildusis E, Smolskas E, Ambrazevicius M, Strupas K Early loop ileostomy;Closure of ileostomyPostoperative complications ;Viszeralmedizin ;2014;30:276-282
[4]. Mritunjay Sarawgi , Sachin K Singh , Arun K Tiwary , Anjay Kumar Early Vs Delayed Loop Ileostomy Closure: A Comparative Study * IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 16, Issue 7 Ver. VI (July. 2017), PP 08-13.

Abstract: Background: Social health insurance provides an efficient and equitable mechanism to achieve universal health coverage and improve the health of populations. These goals cannot be achieved without Continuous Quality Improvement (COQI) ensuring acceptability, patient satisfaction, service utilization and positive health outcomes. A CQI framework and patient centered benchmarking are currently lacking in the NHIS. Aim: to determine the pattern of enrollees' satisfaction with service components, the calculated service gaps and the interaction between the rated satisfaction and importance of service components. Materials and Methods: Three hundred randomly selected participants were studied using the SWOPS and a customized questionnaire in a cross- sectional survey. P value <0.05.......

KeyWords: Health insurance, patient-satisfaction, expectation, experience, service quality

[1]. Hafez R. Nigeria Health Financing System Assessment. Health, Nutrition and Population (HNP) Discussion Paper. 2018 The International Bank for Reconstruction and Development/ The World Bank. Available at documents.worldbank,org> Accessed 15/12/19.[2]. Aregbeshola B. Enhancing Political Will for Universal Health Coverage in Nigeria. Perspectives. Int. Journal of Cuban Health & Medicine19(1) Jan 2017
[3]. Mohammed S., BermejoJ.L., Souares A., SauerbornA., Dong H. Assessing Responsiveness of Health Care Services within a Health Insurance Scheme in Nigeria: User's Perspectives. BMC Health Services Research 2013, 13;502 http://www.biomedcentral.com/1472-6963/13/502
[4]. Osamuyimen A., Ranthamane R., Qifei W. Analysis of Nigeria Health Insurance Scheme: Lessons from China, Germany and United Kingdom. IOSR Journal of Humanities and Social Science Vol 22. DOI: 10.970-/-837-2204013339 www.iosrjournals.org
[5]. Sofaer S., Firminger K. Patient Perceptions of the Quality of Health Services. Annu rev. Public Health 2005. 26:513-59 doi: 10.1146/annurev.publhealth 25.050503.153958..

Abstract: This study aims to evaluate the aetiology, demographic distribution, the clinical presentation of various types of intra abdominal injuries due to blunt injury abdomen, their surgical management, and the clinical outcome. This study is a hospital-based prospective study that includes 60 patients clinically presented as blunt injury abdomen at Emergency Room, Government General Hospital, Guntur and got admitted to surgical ward from the period of September 2018 to August 2019. Data were collected in terms of the causative factor, clinical presentation, followed by appropriate investigations and their management, which included non-operative management......

Keywords: Intra-abdominal injuries; Blunt injury abdomen; Splenectomy; Non-operative management

[1]. Blunt abdominal trauma: evaluation of diagnostic options and surgical outcomes. Karamercan A, Yilmaz TU, Karamercan MA, Aytaç B Ulus Travma Acil Cerrahi Derg. 2008 Jul; 14(3):205-10.
[2]. Computed Tomography (CT) Imaging of Injuries from Blunt Abdominal Trauma: A Pictorial Essay. Hassan R, Abd Aziz A Malays J Med Sci. 2010 Apr; 17(2):29-39.
[3]. Current Trends in the Management of Blunt Solid Organ Injuries. Taviloglu K, Yanar H Eur J Trauma Emerg Surg. 2009 Apr; 35(2):90-4.
[4]. Bailey & Love's short practice of surgery, 27th edition, volume-1, page no-372.
[5]. Mohsin Raza Yasser Abbas, Vanitha Devi, Kumarapuram Venkatachalam Souriaraj an Prasad, Kameel Narouz Rizk Non operative management of abdominal trauma – a 10 years review World Journal of Emergency Surgery 2013, 8:14 doi:10.1186/1749-7922-8-14.

Abstract: A misconception of the sickness by African traditional communities may constitute an obstacle to access quality healthcare and included the precarity of buccodental care in rural areas can facilitate the emergence of sicknesses and their evolutions to complications. The purpose of this report is to portray the first case of a rare large chronic fistula of the jaw of an adult patient who has precarious buccodental hygiene and has received no medical treatment for cultural reasons being observed at Kikungu in the health zone of Kasenga, Haut-Katanga Province, DR. Congo.

Key-words: buccodental hygiene, chronic fistula, DR. Congo

[1]. Newby JD, Aitken WJ. Chronic Fistula of the Mandible. Can Med Assoc J. 15 févr 1964;90(7):492‑3.
[2]. The Perception of Illness in Traditional Africa and the Development of Traditional Medical Practice : International Journal of Nursing [Internet]. Disponible sur: http://ijnnet.com/vol-1-no-1-june-2014-abstract-5-ijn
[3]. Guevara-Gutiérrez E, Riera-Leal L, Gómez-Martínez M, Amezcua-Rosas G, Chávez-Vaca CL, Tlacuilo-Parra A. Odontogeniccutaneousfistulas: clinical and epidemiologiccharacteristics of 75 cases. Int J Dermatol. janv 2015;54(1):50‑5.
[4]. Brown RS, Jones R, Feimster T, Sam FE. Cutaneous sinus tracts (or emerging sinus tracts) of odontogenic origin: a report of 3 cases. Clin Cosmet Investig Dent. 2010;2:63‑7.
[5]. Giménez-García R, Martinez-Vera F, Fuentes-Vera L. Cutaneous Sinus Tracts of Odontogenic Origin: Two Case Reports. J Am Board Fam Med. 11 janv 2015; 28(6):838‑40..

Abstract: Background It is found that higher pH solutions established anaesthesia of better quality [1]. Sodium bicarbonate is alkaline in nature and on infiltrating into an infected space can increase the pH of the surrounding. There are several causes for failure to achieve profound regional anaesthesia. These include inflammation and/or infection, anatomic variation, intravascular injection, accessory innervation, and deflection of the needle. Inflammation and infection reduces the efficacy of a local anaesthetic by reducing its bioavailability. Infection represents an additional factor in anaesthetic performance. Lower tissue pH at the site of infections makes it extremely difficult for the typical la injection to provide adequate anaesthesia[2] . Infected tissue is more acidic which makes it more difficult for the RN conversion to occur.....

Keywords: sodium bicarbonate, acidosis, space infection,odotogenic infection,buffered local anaesthetic agent

[1]. Whitcomb M, Drum M, Reader A, Nusstein J, Beck M. A prospective, randomized, double-blind study of the anesthetic efficacy of sodium bicarbonate buffered 2% lidocaine with 1:100,000 epinephrine in inferior alveolar nerve blocks. Anesthesia Progress. 2010 ;57(2):59-66. DOI: 10.2344/0003-3006-57.2.59
[2]. Ueno T, Tsuchiya H, Mizogami M, Takakura K. Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite. J Inflamm Res. 2008;1:41–48. doi:10.2147/jir.s3982.
[3]. Kattan, Sereen; Karabucak, Bekir; Hersh, Elliot V.; Korostoff, Johnathan M.; and Hunter, Paul, "Do Buffered Local Anesthetics Provide More Successful Anesthesia Over Non-Buffered Solutions in Patients Requiring Dental Therapy? – A Systematic Review & Meta-Analysis." (2017). Dental Theses. 19. http://repository.upenn.edu/dental_theses/19
[4]. Olmedo-Gaya MV, Manzano-Moreno FJ, Muñoz-López JL, Vallecillo-Capilla MF, Reyes-Botella C. Clin Oral Investig. 2018 Dec;22(9):2981-2988. doi: 10.1007/s00784-018-2386-1. Epub 2018 Feb 15.
[5]. TY - JOURAU - Al-Delayme, RaedPY - 2014/02/01SP - e12EP - 6T1 - A comparison of two anesthesia methods for the surgical removal of maxillary third molars: PSA nerve block technique vs. local infiltration techniqueVL - 6DO - 10.4317/jced.51199JO -Journal of clinical and experimental dentistryER.

Abstract: Background:Antimicrobial resistance (AMR) is a threat to the modern world. Enterobacteriaceae, a family encompassing many clinically important bacterial species, exhibits rising levels of AMR. Infection with either extended spectrum b-lactamase-producing Enterobacteriaceae (ESBL-E) or carbapenemase-producing Enterobacteriaceae (CPE) is associated with increased mortality rates, time to effective therapy, length of stay and overall healthcare costs. Materials and Methods:The study was conducted in Department of Microbiology, DM WIMS Medical College, Wayanad during a period of one year. The isolates were identified on the basis of conventional microbiological procedures. Results: The magnitude of ESBL producing GNB was 29.4 % and that of MBL was 8.9%. ConclusionThe study concludes the increase in number of ESBL and MBL producers and effective measures should be taken to reduce mortality among patients due to this rising disaster.

Key Words: ESBL, MBL, Blood isolates, Enterobacteriaceae

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